N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

Base Information

Chemical Name:N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide
CAS No.:1383852-19-4
Molecular Formula:C₂₆H₂₉N₃O₄S
Molecular Weight:479.6
Hs Code.:

Synonyms:N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

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Chemical Property of N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

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Technology Process of N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

There total 3 articles about N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1383852-18-3
N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

: 1383852-19-4
N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

Guidance literature:: With hydrogen; 10 wt% Pd(OH)2 on carbon; In N,N-dimethyl-formamide; for 6h; under 1551.49 Torr;

Reference yield:

: 541-28-6
isopentyl iodide

: 1383852-19-4
N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 24 h

2: hydrogen / 10 wt% Pd(OH)2 on carbon / N,N-dimethyl-formamide / 6 h / 1551.49 Torr

With hydrogen; potassium carbonate; 10 wt% Pd(OH)2 on carbon; In dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 1383852-17-2
N-(2-(4-(benzyloxy)phenyl)-5-cyclopropyl-3-(1H-imidazol-2-yl)benzofuran-6-yl)methanesulfonamide

: 1383852-19-4
N-(5-cyclopropyl-2-(4-hydroxyphenyl)-3-(1H-imidazol-2-yl)benzofuran-6-yl)-N-isopentylmethanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 24 h

2: hydrogen / 10 wt% Pd(OH)2 on carbon / N,N-dimethyl-formamide / 6 h / 1551.49 Torr

With hydrogen; potassium carbonate; 10 wt% Pd(OH)2 on carbon; In dimethyl sulfoxide; N,N-dimethyl-formamide;