Technology Process of N10-nitrosopteroyl azide
There total 5 articles about N10-nitrosopteroyl azide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tert.-butylnitrite; potassium thioacyanate;
In
trifluoroacetic acid;
at -10 ℃;
for 4h;
DOI:10.1021/ja971568j
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrahydrofuran / 10.5 h / 0 - 25 °C
1.2: 123 g / ice / tetrahydrofuran / 3 h / 25 °C
2.1: 89 percent / aq. cesium carbonate / dimethylformamide / 5 h / 25 °C
3.1: 90 percent / hydrazine / dimethylsulfoxide-d6 / 9 h / 25 °C
4.1: potassium thiocyanate; tert-butyl nitrite / trifluoroacetic acid / 4 h / -10 °C
With
tert.-butylnitrite; potassium thioacyanate; caesium carbonate; hydrazine;
In
tetrahydrofuran; dimethylsulfoxide-d6; N,N-dimethyl-formamide; trifluoroacetic acid;
1.1: Acylation / 1.2: Hydrolysis / 2.1: Hydrolysis / 3.1: hydrazinolysis / 4.1: Nitrosation;
DOI:10.1021/ja971568j
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 67 percent / tetramethylguanidine / dimethylsulfoxide / 9 h / 25 °C
2.1: tetrahydrofuran / 10.5 h / 0 - 25 °C
2.2: 123 g / ice / tetrahydrofuran / 3 h / 25 °C
3.1: 89 percent / aq. cesium carbonate / dimethylformamide / 5 h / 25 °C
4.1: 90 percent / hydrazine / dimethylsulfoxide-d6 / 9 h / 25 °C
5.1: potassium thiocyanate; tert-butyl nitrite / trifluoroacetic acid / 4 h / -10 °C
With
tert.-butylnitrite; 1,1,3,3-tetramethylguanidine; potassium thioacyanate; caesium carbonate; hydrazine;
In
tetrahydrofuran; dimethylsulfoxide-d6; dimethyl sulfoxide; N,N-dimethyl-formamide; trifluoroacetic acid;
1.1: Acylation / 2.1: Acylation / 2.2: Hydrolysis / 3.1: Hydrolysis / 4.1: hydrazinolysis / 5.1: Nitrosation;
DOI:10.1021/ja971568j
