C₄₀H₅₈O₇Si

Base Information

Chemical Name:C₄₀H₅₈O₇Si
CAS No.:259258-07-6
Molecular Formula:C₄₀H₅₈O₇Si
Molecular Weight:678.982
Hs Code.:

C<sub>40</sub>H<sub>58</sub>O<sub>7</sub>Si

Synonyms:C₄₀H₅₈O₇Si

Suppliers and Price of C₄₀H₅₈O₇Si

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₀H₅₈O₇Si

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₀H₅₈O₇Si

There total 23 articles about C₄₀H₅₈O₇Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-39-0
benzyl bromide

: 259258-07-6
C₄₀H₅₈O₇Si

Guidance literature:: Multi-step reaction with 10 steps

1.1: 83 percent / sodium hydride / tetrahydrofuran; dimethylformamide; various solvent(s) / 0 - 50 °C

2.1: 77 percent / dimethyl sulfide; BF₃*Et₂O / CH₂Cl₂ / 0.33 h / 0 °C

3.1: 93 percent / 4-(dimethylamino)pyridine; triethylamine / CH₂Cl₂ / 2 h / 0 °C

4.1: 89 percent / dimethylsulfoxide / 5.5 h / 70 °C

5.1: DIBALH / CH₂Cl₂; toluene / 1 h / -78 °C

5.2: 80 percent / benzene / 1 h / 80 °C

6.1: 97 percent / 2,6-lutidine / CH₂Cl₂ / 0.67 h / 0 °C

7.1: 89 percent / DIBALH / CH₂Cl₂; hexane / 0.5 h / -78 °C

8.1: 75 percent / D-(-)-diethyl tartrate; titanium tetraisopropoxide; tert-butyl hydroperoxide / molecular sieves 4A / CH₂Cl₂; 2,2,4-trimethyl-pentane / 5 h / -20 °C

9.1: triethylamine; SO₃*pyridine / CH₂Cl₂; dimethylsulfoxide / 0.5 h / 0 °C

10.1: NaHMDS / tetrahydrofuran / 0.5 h / 0 °C

10.2: 1.081 g / tetrahydrofuran / 0.5 h / 0 °C

With 2,6-dimethylpyridine; titanium(IV) isopropylate; tert.-butylhydroperoxide; dmap; pyridine-SO₃ complex; dimethylsulfide; diethyl (2S,3S)-tartrate; boron trifluoride diethyl etherate; sodium hexamethyldisilazane; sodium hydride; diisobutylaluminium hydride; triethylamine; 4 A molecular sieve; In tetrahydrofuran; 2,2,4-trimethylpentane; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; 1.1: Etherification / 2.1: Hydrolysis / 3.1: Tosylation / 4.1: Substitution / 5.1: Reduction / 5.2: Substitution / 6.1: Etherification / 7.1: Reduction / 8.1: Epoxidation / 9.1: Oxidation / 10.1: Dehydrobromination / 10.2: Substitution;
DOI:10.1021/jo990988j

Reference yield:

: (2R,3R,4R)-5-Allyloxy-2-[(1S,2S)-1-benzyloxy-2-((2R,3R)-3-methoxymethoxymethyl-oxiranyl)-propyl]-4-methyl-tetrahydro-furan-3-ol

: 259258-07-6
C₄₀H₅₈O₇Si

Guidance literature:: Multi-step reaction with 22 steps

1.1: potassium dimsylate / tetrahydrofuran; dimethylsulfoxide / 0 - 20 °C

1.2: 16.64 g / 2,6-lutidine / CH₂Cl₂ / 0 - 20 °C

2.1: [Ir(COD)(Ph₂MeP)2]PF₆; hydrogen / tetrahydrofuran / 0.58 h / 20 °C

2.2: 9.69 g / iodine / tetrahydrofuran; H₂O / 0.08 h / 20 °C

3.1: NaHMDS / tetrahydrofuran / 0.5 h / 0 °C

3.2: 71 percent / tetrahydrofuran / 0 - 20 °C

4.1: 98 percent / pyridinium p-toluenesulfonate / CH₂Cl₂ / 2.5 h / 20 °C

5.1: 9-borabicyclo[3.3.1]nonane / tetrahydrofuran / 0 - 20 °C

5.2: 9.90 g / hydrogen peroxide; sodium hydroxide / tetrahydrofuran / 1.5 h / 20 °C

6.1: triethylamine; SO₃*pyridine / CH₂Cl₂; dimethylsulfoxide / 0.5 h / 0 °C

7.1: acetic acid / tetrahydrofuran; H₂O / 20 °C

8.1: 6.98 g / pyridinium dichromate; molecular sieves 4A / CH₂Cl₂ / 2 h / 20 °C

9.1: LiHMDS / tetrahydrofuran; hexane / 0.5 h / -78 °C

9.2: 92 percent / tetrahydrofuran; hexane / -78 - 0 °C

10.1: 79 percent / tetrahydrofuran; diethyl ether / 0.75 h / -78 °C

11.1: N,N'-bis(2,4,6-Me₃C₆H₂CH₂)-(S,S)-1,2-Ph₂-1,2-diaminoethane; osmium tetroxide / CH₂Cl₂ / 2 h / -90 °C

11.2: 85 percent / NaHSO₃ / tetrahydrofuran; H₂O / 2 h / Heating

12.1: 86 percent / camphorsulfonic acid / benzene / 36 h / 20 °C

13.1: 83 percent / sodium hydride / tetrahydrofuran; dimethylformamide; various solvent(s) / 0 - 50 °C

14.1: 77 percent / dimethyl sulfide; BF₃*Et₂O / CH₂Cl₂ / 0.33 h / 0 °C

15.1: 93 percent / 4-(dimethylamino)pyridine; triethylamine / CH₂Cl₂ / 2 h / 0 °C

16.1: 89 percent / dimethylsulfoxide / 5.5 h / 70 °C

17.1: DIBALH / CH₂Cl₂; toluene / 1 h / -78 °C

17.2: 80 percent / benzene / 1 h / 80 °C

18.1: 97 percent / 2,6-lutidine / CH₂Cl₂ / 0.67 h / 0 °C

19.1: 89 percent / DIBALH / CH₂Cl₂; hexane / 0.5 h / -78 °C

20.1: 75 percent / D-(-)-diethyl tartrate; titanium tetraisopropoxide; tert-butyl hydroperoxide / molecular sieves 4A / CH₂Cl₂; 2,2,4-trimethyl-pentane / 5 h / -20 °C

21.1: triethylamine; SO₃*pyridine / CH₂Cl₂; dimethylsulfoxide / 0.5 h / 0 °C

22.1: NaHMDS / tetrahydrofuran / 0.5 h / 0 °C

22.2: 1.081 g / tetrahydrofuran / 0.5 h / 0 °C

With 2,6-dimethylpyridine; titanium(IV) isopropylate; tert.-butylhydroperoxide; dmap; osmium(VIII) oxide; dipyridinium dichromate; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; pyridine-SO₃ complex; dimethylsulfide; diethyl (2S,3S)-tartrate; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; hydrogen; sodium hexamethyldisilazane; pyridinium p-toluenesulfonate; potassium dimsylate; sodium hydride; diisobutylaluminium hydride; acetic acid; (1S,2S)-1,2-diphenyl-N¹,N²-bis(mesitylmethyl)ethane-1,2-diamine; triethylamine; 9-bora-bicyclo[3.3.1]nonane; lithium hexamethyldisilazane; 4 A molecular sieve; In tetrahydrofuran; 2,2,4-trimethylpentane; diethyl ether; hexane; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; benzene; 1.1: Cyclization / 1.2: Etherification / 2.1: Hydrolysis / 2.2: Hydrolysis / 3.1: Dehydrobromination / 3.2: methylenation; Wittig reaction / 4.1: Addition / 5.1: hydroboration / 5.2: Oxidation / 6.1: Oxidation / 7.1: Hydrolysis / 8.1: Oxidation / 9.1: Metallation / 9.2: Methylation / 10.1: Addition / 11.1: Oxidation / 11.2: Ring cleavage / 12.1: Cyclization / 13.1: Etherification / 14.1: Hydrolysis / 15.1: Tosylation / 16.1: Substitution / 17.1: Reduction / 17.2: Substitution / 18.1: Etherificat;
DOI:10.1021/jo990988j

Reference yield:

: 157220-15-0
(2R,3S,4S,5S,6R,7S)-4-Benzyloxy-7-methoxymethoxymethyl-5-methyl-2-((S)-1-methyl-allyl)-6-triisopropylsilanyloxy-oxepan-3-ol

: 259258-07-6
C₄₀H₅₈O₇Si

Guidance literature:: Multi-step reaction with 19 steps

1.1: 98 percent / pyridinium p-toluenesulfonate / CH₂Cl₂ / 2.5 h / 20 °C

2.1: 9-borabicyclo[3.3.1]nonane / tetrahydrofuran / 0 - 20 °C

2.2: 9.90 g / hydrogen peroxide; sodium hydroxide / tetrahydrofuran / 1.5 h / 20 °C

3.1: triethylamine; SO₃*pyridine / CH₂Cl₂; dimethylsulfoxide / 0.5 h / 0 °C

4.1: acetic acid / tetrahydrofuran; H₂O / 20 °C

5.1: 6.98 g / pyridinium dichromate; molecular sieves 4A / CH₂Cl₂ / 2 h / 20 °C

6.1: LiHMDS / tetrahydrofuran; hexane / 0.5 h / -78 °C

6.2: 92 percent / tetrahydrofuran; hexane / -78 - 0 °C

7.1: 79 percent / tetrahydrofuran; diethyl ether / 0.75 h / -78 °C

8.1: N,N'-bis(2,4,6-Me₃C₆H₂CH₂)-(S,S)-1,2-Ph₂-1,2-diaminoethane; osmium tetroxide / CH₂Cl₂ / 2 h / -90 °C

8.2: 85 percent / NaHSO₃ / tetrahydrofuran; H₂O / 2 h / Heating

9.1: 86 percent / camphorsulfonic acid / benzene / 36 h / 20 °C

10.1: 83 percent / sodium hydride / tetrahydrofuran; dimethylformamide; various solvent(s) / 0 - 50 °C

11.1: 77 percent / dimethyl sulfide; BF₃*Et₂O / CH₂Cl₂ / 0.33 h / 0 °C

12.1: 93 percent / 4-(dimethylamino)pyridine; triethylamine / CH₂Cl₂ / 2 h / 0 °C

13.1: 89 percent / dimethylsulfoxide / 5.5 h / 70 °C

14.1: DIBALH / CH₂Cl₂; toluene / 1 h / -78 °C

14.2: 80 percent / benzene / 1 h / 80 °C

15.1: 97 percent / 2,6-lutidine / CH₂Cl₂ / 0.67 h / 0 °C

16.1: 89 percent / DIBALH / CH₂Cl₂; hexane / 0.5 h / -78 °C

17.1: 75 percent / D-(-)-diethyl tartrate; titanium tetraisopropoxide; tert-butyl hydroperoxide / molecular sieves 4A / CH₂Cl₂; 2,2,4-trimethyl-pentane / 5 h / -20 °C

18.1: triethylamine; SO₃*pyridine / CH₂Cl₂; dimethylsulfoxide / 0.5 h / 0 °C

19.1: NaHMDS / tetrahydrofuran / 0.5 h / 0 °C

19.2: 1.081 g / tetrahydrofuran / 0.5 h / 0 °C

With 2,6-dimethylpyridine; titanium(IV) isopropylate; tert.-butylhydroperoxide; dmap; osmium(VIII) oxide; dipyridinium dichromate; pyridine-SO₃ complex; dimethylsulfide; diethyl (2S,3S)-tartrate; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; sodium hexamethyldisilazane; pyridinium p-toluenesulfonate; sodium hydride; diisobutylaluminium hydride; acetic acid; (1S,2S)-1,2-diphenyl-N¹,N²-bis(mesitylmethyl)ethane-1,2-diamine; triethylamine; 9-bora-bicyclo[3.3.1]nonane; lithium hexamethyldisilazane; 4 A molecular sieve; In tetrahydrofuran; 2,2,4-trimethylpentane; diethyl ether; hexane; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene; benzene; 1.1: Addition / 2.1: hydroboration / 2.2: Oxidation / 3.1: Oxidation / 4.1: Hydrolysis / 5.1: Oxidation / 6.1: Metallation / 6.2: Methylation / 7.1: Addition / 8.1: Oxidation / 8.2: Ring cleavage / 9.1: Cyclization / 10.1: Etherification / 11.1: Hydrolysis / 12.1: Tosylation / 13.1: Substitution / 14.1: Reduction / 14.2: Substitution / 15.1: Etherification / 16.1: Reduction / 17.1: Epoxidation / 18.1: Oxidation / 19.1: Dehydrobromination / 19.2: Substitution;
DOI:10.1021/jo990988j