phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

Base Information

• Chemical Name: phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate
• CAS No.: 1055912-61-2
• Molecular Formula: C₃₁H₂₅NO₆
• Molecular Weight: 507.543
• Mol file: 1055912-61-2.mol

Synonyms:phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

Chemical Property of phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

There total 3 articles about phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-oxazolyl-5-yl phenyl carbonate (1060771-73-4) → phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate (1055912-61-2)

Guidance literature:

With 3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine; In dichloromethane; at 20 - 25 ℃; for 0.25h;

DOI:10.1039/b805850d

Reference yield: 84.0%

DL-N-(4-methoxybenzoyl)-O-benzyltyrosine (1055912-55-4) + phenyl chloroformate (1885-14-9) → phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate (1055912-61-2)

Guidance literature:

DL-N-(4-methoxybenzoyl)-O-benzyltyrosine; With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃; for 2h;

phenyl chloroformate; With 2-phenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; triethylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/c1ob05160a

Reference yield: 81.0%

4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole (1055912-40-7) + phenyl chloroformate (1885-14-9) → phenyl 4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate (1055912-61-2)

Guidance literature:

With 2-phenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; triethylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/b806816j

upstream raw materials:

4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole

phenyl chloroformate

4-(4-(benzyloxy)benzyl)-2-(4-methoxyphenyl)-oxazolyl-5-yl phenyl carbonate

DL-N-(4-methoxybenzoyl)-O-benzyltyrosine