Ethyl 4-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrrole-2-carboxylate

Base Information

Chemical Name:Ethyl 4-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrrole-2-carboxylate
CAS No.:126760-73-4
Molecular Formula:C₁₇H₂₁NO₂
Molecular Weight:271.359
Hs Code.:
DSSTox Substance ID:DTXSID201169655
Nikkaji Number:J1.522.975F

Synonyms:DTXSID201169655;126760-73-4;Ethyl 4-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrrole-2-carboxylate

Suppliers and Price of Ethyl 4-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrrole-2-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 4-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrrole-2-carboxylate

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:271.157228913
Heavy Atom Count:20
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=CN1)C)C2=C(C=C(C=C2C)C)C

Technology Process of Ethyl 4-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrrole-2-carboxylate

There total 2 articles about Ethyl 4-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrrole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2999-46-4
Ethyl isocyanoacetate

: 126760-70-1
1-(2,4,6-Trimethyl-phenyl)-2-nitro-propen

: 126760-73-4
ethyl 4-methyl-3-mesitylpyrrole-2-carboxylate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 25 ℃; for 24h;
DOI:10.1016/S0040-4020(01)89062-1 DOI:10.1039/c39890001580

Reference yield:

: 487-68-3
mesytaldehyde

: 126760-73-4
ethyl 4-methyl-3-mesitylpyrrole-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: CH₃CO₂K, CH₃NH₂*HCl, methyl orthoformate / methanol / Heating

2: DBU / tetrahydrofuran / 24 h / 25 °C

With methylamine hydrochloride; potassium acetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; trimethyl orthoformate; In tetrahydrofuran; methanol;
DOI:10.1016/S0040-4020(01)89062-1

Reference yield: 40.0%

: 126760-73-4
ethyl 4-methyl-3-mesitylpyrrole-2-carboxylate

: 126760-82-5
3,8,13,18-tetramesityl-2,7,12,17-tetramethylporphyrin

Guidance literature:: ethyl 4-methyl-3-mesitylpyrrole-2-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2h;

With Montmorillonite K₁₀; In chloroform;

With chloranil; In chloroform; for 15h;