Cinnamyl Benzoylcarbamate

Base Information

• Chemical Name: Cinnamyl Benzoylcarbamate
• CAS No.: 129217-44-3
• Molecular Formula: C₁₇H₁₅NO₃
• Molecular Weight: 281.311
• Mol file: 129217-44-3.mol

Synonyms:Cinnamyl Benzoylcarbamate

Chemical Property of Cinnamyl Benzoylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of Cinnamyl Benzoylcarbamate

There total 1 articles about Cinnamyl Benzoylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(2E)-3-phenyl-2-propen-1-ol (4407-36-7) + benzoyl isocyanate (4461-33-0) → Cinnamyl Benzoylcarbamate (129217-44-3)

Guidance literature:

In tetrachloromethane; at 25 ℃;

DOI:10.1021/jo00309a013

Reference yield: 90.0%

Cinnamyl Benzoylcarbamate (129217-44-3) → 3-phenyl-2(R*),3(R*)-epoxypropyl benzoylcarbamate (129217-17-0)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 25 ℃; for 12h;

DOI:10.1021/jo00309a013

Reference yield:

Cinnamyl Benzoylcarbamate (129217-44-3) → 4(R*)-<(S*)-hydroxy(phenyl)methyl>-1,3-oxazolin-2-one (129217-19-2)

Guidance literature:

Multi-step reaction with 3 steps

1: mCPBA / CH₂Cl₂ / 25 °C

2: 88 percent / NaH / tetrahydrofuran / Heating

3: 85 percent / LiOH / H₂O; tetrahydrofuran / 25 °C

With lithium hydroxide; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/S0040-4039(00)96738-8

upstream raw materials:

(2E)-3-phenyl-2-propen-1-ol

benzoyl isocyanate

Downstream raw materials:

3-phenyl-2(R*),3(R*)-epoxypropyl benzoylcarbamate

4(R*)-<(S*)-hydroxy(phenyl)methyl>-1,3-oxazolin-2-one

(2-oxooxazolidin-4-yl)(phenyl)methyl benzoate