C₂₁H₂₃NO₅

Base Information

• Chemical Name: C₂₁H₂₃NO₅
• CAS No.: 1429413-04-6
• Molecular Formula: C₂₁H₂₃NO₅
• Molecular Weight: 369.417
• Mol file: 1429413-04-6.mol

Synonyms:C₂₁H₂₃NO₅

Chemical Property of C₂₁H₂₃NO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₂₃NO₅

There total 3 articles about C₂₁H₂₃NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R,R,R,R)-4-benzyloxy-5-[N-benzyl-N-(α-methylbenzyl)amino]-6-(triisopropylsilyloxy)hex-1-en-3-ol (1429412-85-0) + sodium hydrogencarbonate (144-55-8) → C21H23NO5 (1429413-04-6)

Guidance literature:

(R,R,R,R)-4-benzyloxy-5-[N-benzyl-N-(α-methylbenzyl)amino]-6-(triisopropylsilyloxy)hex-1-en-3-ol; sodium hydrogencarbonate; With iodine; In 1,4-dioxane; water; at 20 ℃; for 16h;

With pyridine hydrogenfluoride; In tetrahydrofuran; at 0 - 20 ℃; for 16h;

DOI:10.1021/ol400735z

Reference yield:

2-benzyloxy-3-[N-benzyl-N-(α-methylbenzyl)amino]-4-(triisopropylsilyloxy)butanal (1429412-84-9) → C21H23NO5 (1429413-04-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere

2.1: iodine / water; 1,4-dioxane / 16 h / 20 °C

2.2: 16 h / 0 - 20 °C

With iodine; In tetrahydrofuran; 1,4-dioxane; water;

DOI:10.1021/ol400735z

Reference yield:

C35H51NO3Si (1429412-83-8) → C21H23NO5 (1429413-04-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 0.5 h / -78 °C

1.2: 0.5 h / -78 °C

2.1: tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere

3.1: iodine / water; 1,4-dioxane / 16 h / 20 °C

3.2: 16 h / 0 - 20 °C

With oxalyl dichloride; iodine; dimethyl sulfoxide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water;

DOI:10.1021/ol400735z

upstream raw materials:

2-benzyloxy-3-[N-benzyl-N-(α-methylbenzyl)amino]-4-(triisopropylsilyloxy)butanal

C₃₅H₅₁NO₃Si

(R,R,R,R)-4-benzyloxy-5-[N-benzyl-N-(α-methylbenzyl)amino]-6-(triisopropylsilyloxy)hex-1-en-3-ol

sodium hydrogencarbonate

Downstream raw materials:

1-deoxymannojirimycin