Sodium bicarbonate

Base Information

• Chemical Name: Sodium bicarbonate
• CAS No.: 144-55-8
• Molecular Formula: NaHCO3
• Molecular Weight: 84.0069
• Hs Code.: 28363000
• Mol file: 144-55-8.mol

Synonyms:Carbonic acid, monosodium salt;Natriumhydrogenkarbonat;Meylon;Carbonic acid disodium salt;SodaSee;Monosodium hydrogen carbonate;Monosodium carbonate;monosodium salt ;; see the subdivided heading;Component of Col-Evac;Soda Mint;Sodium bicarbonate(1:1);Carbonic acid, disodium salt;Natriumbicarbonat, Natriumhydrogencarbonat;Sodium Bicarbonate food grade;

Chemical Property of Sodium bicarbonate

Chemical Property:

• Appearance/Colour: white powder or crystals
• Vapor Pressure: 2.58E-05mmHg at 25°C
• Melting Point: 50 °C, 323 K, 122 °F (decomposes)
• Refractive Index: 1.500
• Boiling Point: 333.6 °C at 760 mmHg
• PKA: (1) 6.37, (2) 10.25 (carbonic (at 25℃)
• Flash Point: 169.8 °C
• PSA: 60.36000
• Density: 2.173 g/cm³
• LogP: -1.11230
• Storage Temp.: 2-8°C
• Solubility.: H2O: 1 M at 20 °C, clear, colorless
• Water Solubility.: 9 g/100 mL (20 ºC)

Purity/Quality:

99.5% ^*data from raw suppliers

Sodium Bicarbonate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Historical Research: Research on the effects of sodium bicarbonate on exercise performance dates back to the 1930s. Early studies demonstrated improved performance with pre-exercise alkalosis induced by sodium bicarbonate ingestion. Notably, a landmark study in 1977 by Jones et al. showed that participants cycled significantly longer to exhaustion after ingesting sodium bicarbonate compared to control conditions.
• Industrial Applications: Sodium bicarbonate is used in various industrial sectors, including chemical, food, textile, and pharmaceutical industries. Its production from CO2 capture and reuse has gained importance due to environmental concerns. Raw materials like sodium chloride, sodium carbonate, and sodium sulfate are commonly used in its production process.
• Medical Uses: Sodium bicarbonate serves as an antacid for relieving heartburn and acid indigestion. Additionally, it is employed in prescription and over-the-counter medications for various purposes.
• Ergogenic Aid: Studies have explored the effects of sodium bicarbonate on exercise performance across different modes of exercise, including combat sports, resistance exercise, and high-intensity cycling, running, swimming, and rowing. Sodium bicarbonate is used as an ergogenic aid in these contexts.
• Solubility and Dissociation: Sodium bicarbonate is highly soluble in water, dissociating promptly into sodium (Na+) and bicarbonate (HCO3-) ions upon contact with aqueous solutions, such as stomach acid. This dissociation process contributes to its physiological effects.
• Physiological Effects: Upon ingestion, sodium bicarbonate reacts with stomach acid, leading to the formation of carbon dioxide (CO2), which is then released from the gastric juice through belching. Despite some bicarbonate being neutralized by stomach acid, it alkalizes gastric juice, stimulating bicarbonate transport into the blood through cellular mechanisms.
• Dosage and Timing: Studies typically use a dose of 0.3 g/kg of body weight of sodium bicarbonate, administered approximately 3 hours before exercise. This dosage and timing have become standard in research examining the effects of sodium bicarbonate on exercise performance.
• Significance in Exercise Physiology: Research on sodium bicarbonate's effects on exercise performance has had a significant impact on the field of exercise physiology, contributing to our understanding of buffering capacity, acid-base balance, and strategies for enhancing athletic performance.

Technology Process of Sodium bicarbonate

There total 170 articles about Sodium bicarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

CYANAMID (420-04-2) + sodium hydroxide (1310-73-2) → sodium cyanamide (19981-17-0,20611-81-8,123092-13-7,17292-62-5) + sodium hydrogencarbonate (144-55-8)

Guidance literature:

In methanol; after N. A. Gol'dberg and V. G. Golov, Zh. Prikl. Khim., 35, 2106 (1962);

Reference yield: 30.0%

Na(1+)*H(1+)*W2(CO)10(2-)=NaHW2(CO)10 → triphenylphosphine tungsten pentacarbonyl (15444-65-2) + trans-triphenylphosphane tetracarbonyltungsten (16743-03-6,38800-77-0,68738-00-1) + sodium formate (141-53-7) + sodium hydrogencarbonate (144-55-8) + sodium carbonate (497-19-8)

Guidance literature:

With carbon dioxide; triphenylphosphine; In acetonitrile; Irradiation (UV/VIS); (Ar or N2); UV irradn. (>420 nm) of soln. of W compd. and PPh3 with stirring at ca. 20°C for ca. 12 h under CO2 pressure, formed ppt. was sepd.; W compds. were detected IR spect. in filtrate, not isolated; NaHCOO detected 1HNMR spect. in D2O soln. of ppt.; Na2CO3 and NaHCO3 detd. in aq. soln. of ppt. by titrn.;

Reference yield:

Sodium borate + carbonic-acid (463-79-6) → metaboric acid (13460-50-9) + sodium hydrogencarbonate (144-55-8)

Guidance literature:

In water; equilibrium reaction;;

upstream raw materials:

1,3,5-trichloro-2,4,6-triazine

(1-carbamoylmethyl-cyclohexylmethyl)-carbamic acid tert-butyl ester

5-[N-tert-butoxycarbonyl-N-[5-(trifluoromethanesulfonamido)pentan-1-yl]aminomethyl]-imidazo[1,2-a]pyridine

trifluoroacetyl chloride

Downstream raw materials:

carboxybiotin

carbon dioxide

(R)-(+)-4-vinyl-1,3-dioxolan-2-one

(S)-4-vinyl-1,3-dioxolan-2-one

Refernces

• 1、 Oglesby, N. E.. "-". . p. 2352 - 2362. Retrieved 1929.
• 2、 Liebing, Phil,Schmeide, Marten,Kühling, Marcel,Witzorke, Juliane. "The Alkali Metal Salts of Methyl Xanthic Acid". . p. 2428 - 2434. Retrieved 2020.
• 3、 Wegscheidep, R.,Mehl, J.. "". . . Retrieved 1928.
• 4、 Galven, Cyrille,Pagnier, Thierry,Rosman, No?l,Le Berre, Fran?oise,Crosnier-Lopez, Marie-Pierre. "β-Na2TeO4: Phase Transition from an Orthorhombic to a Monoclinic Form. Reversible CO2 Capture". . p. 7334 - 7345. Retrieved 2018.
• 5、 Barrett, Seth M.,Slattery, Samuel A.,Miller, Alexander J. M.. "Photochemical Formic Acid Dehydrogenation by Iridium Complexes: Understanding Mechanism and Overcoming Deactivation". . p. 6320 - 6327. Retrieved 2015.
• 6、 -. "CATALYTIC CONVERSION OF CARBON DIOXIDE TO METHANOL". Page/Page column 25; 26. . Retrieved 2019/10/29.