Technology Process of methyl 4,5-diamino-2-hydroxybenzoate
There total 10 articles about methyl 4,5-diamino-2-hydroxybenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl 4-amino-2-hydroxy-5-nitrobenzoate;
With
hydrogenchloride; iron;
In
methanol; water;
for 2h;
Reflux;
With
sodium hydrogencarbonate;
In
water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sulfuric acid / ethanol / 24 h / Reflux
2: triethylamine / tetrahydrofuran / 0 - 26 °C
3: sodium methylate / methanol; water / 0 - 26 °C
4: aluminum (III) chloride / 1,2-dichloro-ethane / Reflux
5: hydrogenchloride; iron / methanol; water / 2 h / Reflux
With
hydrogenchloride; aluminum (III) chloride; sodium methylate; iron; triethylamine;
sulfuric acid;
In
tetrahydrofuran; methanol; ethanol; water; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sulfuric acid; nitric acid / water / 14 h / 0 - 5 °C
2: sulfuric acid / ethanol / 24 h / Reflux
3: triethylamine / tetrahydrofuran / 0 - 26 °C
4: sodium methylate / methanol; water / 0 - 26 °C
5: aluminum (III) chloride / 1,2-dichloro-ethane / Reflux
6: hydrogenchloride; iron / methanol; water / 2 h / Reflux
With
hydrogenchloride; aluminum (III) chloride; sulfuric acid; nitric acid; sodium methylate; iron; triethylamine;
sulfuric acid;
In
tetrahydrofuran; methanol; ethanol; water; 1,2-dichloro-ethane;
