rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

Base Information

Chemical Name:rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate
CAS No.:1209495-01-1
Molecular Formula:C₁₁H₁₀F₃NO₃S
Molecular Weight:293.267
Hs Code.:

Synonyms:rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

Suppliers and Price of rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

There total 2 articles about rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 121054-03-3
2-hydroxy-4-phenylbutanenitrile

: 1209495-01-1
rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at -78 ℃; for 2h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.7b03279

Reference yield:

: 104-53-0
3-phenyl-propionaldehyde

: 1209495-01-1
rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 1,3-bis(mesityl)imidazolium chloride; potassium tert-butylate / tetrahydrofuran / 0.17 h / 20 °C / Schlenk technique; Inert atmosphere

2: 2,6-dimethylpyridine / dichloromethane / 2 h / -78 °C / Schlenk technique; Inert atmosphere

With 2,6-dimethylpyridine; potassium tert-butylate; 1,3-bis(mesityl)imidazolium chloride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.orglett.7b03279

Reference yield: 98.0%

: 1209495-01-1
rac-1-cyano-3-phenylpropyl trifluoromethanesulfonate

: 1226495-17-5
2-fluoro-4-phenylbutanenitrile

Guidance literature:: With potassium fluoride; CH₃I*Cu⁽¹⁺⁾*Cl^(1-); In 1,4-dioxane; at 100 ℃; for 0.166667h; chemoselective reaction; Inert atmosphere; Glovebox;
DOI:10.1002/anie.201402238