2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

Base Information

Chemical Name:2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine
CAS No.:1337568-67-8
Molecular Formula:C₂₂H₃₂FNO₂
Molecular Weight:361.5
Hs Code.:

Synonyms:2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

Suppliers and Price of 2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

There total 2 articles about 2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1513-65-1
2,6-difluoro pyridine

: 1337568-65-6
C₁₇H₃₀O₂

: 1337568-67-8
2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

Guidance literature:: C₁₇H₃₀O₂; With sodium hydride; In dimethyl sulfoxide; mineral oil; at 20 ℃; for 0.333333h; Inert atmosphere;

2,6-difluoro pyridine; In dimethyl sulfoxide; mineral oil; at 20 ℃; Inert atmosphere;
DOI:10.1021/ol202399c

Reference yield:

: 17283-81-7
4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on

: 1337568-67-8
2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: tert.-butyl lithium / tetrahydrofuran / -78 - 0 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: sodium hydride / dimethyl sulfoxide; mineral oil / 0.33 h / 20 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

With tert.-butyl lithium; sodium hydride; In tetrahydrofuran; dimethyl sulfoxide; mineral oil;
DOI:10.1021/ol202399c

Reference yield: 70.0%

: 49762-80-3
O-ethyl S-2-oxopropyl carbonodithioate

: 1337568-67-8
2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine

: 1337568-79-2
6-methyl-8-(2,6,6-trimethylcyclohex-1-en-1-yl)octane-2,5-dione

Guidance literature:: O-ethyl S-2-oxopropyl carbonodithioate; 2-[2-ethoxy-3-methyl-5-(2,6,6-trimethylcyclohex-1-en-1-yl)pent-1-en-3-yl]-6-fluoropyridine; With dilauryl peroxide; In ethyl acetate; Inert atmosphere; Reflux;

With hydrogenchloride; water; In ethyl acetate; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ol202399c