N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride

Base Information

Chemical Name:N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride
CAS No.:1137153-73-1
Molecular Formula:C₁₅H₂₁F₃N₂O₂S*ClH
Molecular Weight:386.866
Hs Code.:

Synonyms:N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride

Chemical Property:

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Technology Process of N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride

There total 3 articles about N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 943223-57-2
C₂₀H₂₉F₃N₂O₄S

: 1137153-73-1
N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; at 20 ℃; for 48h;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 1137153-73-1
N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 24 h / 0 - 20 °C / Molecular sieve

2: triethylamine / dichloromethane / 48 h / 20 - 37 °C

3: hydrogenchloride; water / 1,4-dioxane / 48 h / 20 °C

With hydrogenchloride; water; sodium tris(acetoxy)borohydride; triethylamine; In 1,4-dioxane; dichloromethane; 1,2-dichloro-ethane;

Reference yield:

: 534595-51-2
tert-butyl 4-(isopropylamino)piperidine-1-carboxylate

: 1137153-73-1
N-isopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 48 h / 20 - 37 °C

2: hydrogenchloride; water / 1,4-dioxane / 48 h / 20 °C

With hydrogenchloride; water; triethylamine; In 1,4-dioxane; dichloromethane;