S-(3-amino-2-methyl-3-oxopropyl)ethanethioate

Base Information

• Chemical Name: S-(3-amino-2-methyl-3-oxopropyl)ethanethioate
• CAS No.: 909027-82-3
• Molecular Formula: C₆H₁₁NO₂S
• Molecular Weight: 161.225
• Hs Code.: 2930909899
• Mol file: 909027-82-3.mol

Synonyms:S-(3-amino-2-methyl-3-oxopropyl)ethanethioate

Chemical Property of S-(3-amino-2-methyl-3-oxopropyl)ethanethioate

Chemical Property:

• Boiling Point: 321.7±25.0 °C(Predicted)
• Density: 1.152±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

3-(Acetylsulfanyl)-2-methylpropanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-(3-amino-2-methyl-3-oxopropyl)ethanethioate

There total 1 articles about S-(3-amino-2-methyl-3-oxopropyl)ethanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Methacrylamide (79-39-0) + tiolacetic acid (507-09-5) → S-(3-amino-2-methyl-3-oxopropyl)ethanethioate (909027-82-3)

Guidance literature:

With triethylamine; In dichloromethane; for 12h; Inert atmosphere; Reflux;

DOI:10.1002/hlca.201200547

Reference yield: 34.5%

S-(3-amino-2-methyl-3-oxopropyl)ethanethioate (909027-82-3) → (R)-(+)-3-acetylthio-2-methylpropionamide + (R)-3-acetylsulfanyl-2-methyl-propionic acid (74431-52-0)

Guidance literature:

With recombinant esterase IFO₁₂₉₉₆ from Pseudomonas putida; In water; at 57 ℃; pH=9.0; Further Variations:; pH-values; Temperatures; Enzyme kinetics;

DOI:10.1002/jccs.200700227

upstream raw materials:

Methacrylamide

tiolacetic acid

Downstream raw materials:

(R)-3-acetylsulfanyl-2-methyl-propionic acid

Refernces

• 1、 Shaw, Shyh-Yu,Chen, Yu-Jen,Ou, Jung-Jung,Ho, Lewis. "Steroselective hydrolysis of DL-beta-acetylthioisobutyramide catalyzed by genetically engineered E. coli immobilized on Celite 580 in a packed bed bioreactor". . p. 1607 - 1613. Retrieved 2008/09/16.