(2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol

Base Information

Chemical Name:(2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol
CAS No.:871348-16-2
Molecular Formula:C₂₀H₂₈O₆S
Molecular Weight:396.505
Hs Code.:

Synonyms:(2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol

Suppliers and Price of (2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol

Chemical Property:

Purity/Quality:: 95-428%min ^*data from raw suppliers

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Technology Process of (2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol

There total 10 articles about (2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 871348-10-6
(2R,3R,4R,5S)-5-allyl-2-[(S)-2,3-dihydroxypropyl]-4-[(phenylsulfonyl)methyl]tetrahydrofuran-3-ol

: 116-11-0
2-Methoxypropene

: 871348-16-2
(2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol

Guidance literature:: With sulfuric acid; In 1,2-dimethoxyethane; at 40 ℃;
DOI:10.1055/s-0032-1317920

Reference yield:

: 56069-39-7
diethyl phenylsulfonylmethylphosphonate

: 871348-16-2
(2R,3R,4R,5S)-5-allyl-2-(((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-4-((phenylsulfonyl)methyl)tetrahydrofuran-3-ol

Guidance literature:: Multi-step reaction with 5 steps

1: lithium hexamethyldisilazane / toluene; tetrahydrofuran / 0 - 20 °C

2: trimethylsilyl iodide / toluene; acetonitrile / 60 °C

3: sodium tris(acetoxy)borohydride; tetrabutyl-ammonium chloride / toluene; 1,2-dimethoxyethane / 80 °C

4: potassium carbonate / methanol / 50 °C

5: sulfuric acid / 1,2-dimethoxyethane / 40 °C

With trimethylsilyl iodide; sulfuric acid; tetrabutyl-ammonium chloride; sodium tris(acetoxy)borohydride; potassium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; toluene; acetonitrile;
DOI:10.1055/s-0032-1317920