(S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane

Base Information

• Chemical Name: (S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane
• CAS No.: 1061228-16-7
• Molecular Formula: C₁₇H₂₂O₃
• Molecular Weight: 274.36
• Mol file: 1061228-16-7.mol

Synonyms:(S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane

Chemical Property of (S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane

There total 1 articles about (S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(1S,Z)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)penta-2,4-dien-1-ol (1061227-99-3) + benzyl bromide (100-39-0) → (S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane (1061228-16-7)

Guidance literature:

(1S,Z)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)penta-2,4-dien-1-ol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol8018874

Reference yield: 85.0%

(S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane (1061228-16-7) → (4S,Z)-4-(benzyloxy)-4-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)but-2-enal (1061228-19-0)

Guidance literature:

(S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane; With osmium(VIII) oxide; water; In tetrahydrofuran; at 24 - 26 ℃; for 0.0833333h; Inert atmosphere;

With sodium periodate; In tetrahydrofuran; water; at 25 ℃; for 2.66667h; Inert atmosphere;

DOI:10.1021/ol8018874

Reference yield: 82.0%

(S)-4-((S,Z)-1-(benzyloxy)penta-2,4-dienyl)-2,2-dimethyl-1,3-dioxolane (1061228-16-7) → <4S,4(1S)>-4-<1-(Benzyloxy)pentyl>-2,2-dimethyl-1,3-dioxolane (131446-97-4)

Guidance literature:

With Crabtree's catalyst; hydrogen; In dichloromethane; at 25 ℃; for 12h; under 760.051 Torr;

DOI:10.1021/ol8018874

upstream raw materials:

(1S,Z)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)penta-2,4-dien-1-ol

benzyl bromide

Downstream raw materials:

(4S,Z)-4-(benzyloxy)-4-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)but-2-enal

<4S,4(1S)>-4-<1-(Benzyloxy)pentyl>-2,2-dimethyl-1,3-dioxolane