131446-97-4Relevant academic research and scientific papers
Catalyst-directed diastereoselectivity in hydrogenative couplings of acetylene to α-chiral aldehydes: Formal synthesis of all eight L-hexoses
Man, Soo Bong,Kong, Jong Rock,Krische, Michael J.
supporting information; experimental part, p. 4133 - 4135 (2009/05/27)
(Chemical Equation Presented) Hydrogenative coupling of acetylene to α-chiral aldehydes 1a-4a using enantiomeric rhodium catalysts ligated by (S)-MeO-BIPHEP and (R)-MeO-BIPHEP delivers the diastereomeric products of carbonyl-(Z)-buladienylation 1b-4b and 1c-4c, respectively, with good to excellent levels of catalyst directed diastereofacial selectivity. Diastereomeric L-glyceraldehyde acetonide adducts 1b and 1c were converted to the four isomeric enoates 6b, 8b, 6c, and 8c, representing a formal synthesis of all eight L-hexoses.
Total Synthesis of (+)-Monomorine I via Nitrone Cycloaddition Route
Ito, Masayuki,Kibayashi, Chihiro
, p. 9329 - 9350 (2007/10/02)
An enantioselective total synthesis of (+)-monomorine I (1) is described.The key feature of the synthesis is the asymmetric 1,3-dipolar cycloaddition of the prochiral nitrone 9 with the chiral (S)-allylic ether 8 as a dipolarophile, which provides stereos
An alternative enantioselective total synthesis of (+)-monomorine I
Ito,Kibayashi
, p. 5065 - 5068 (2007/10/02)
An alternative enantioselective total synthesis of (+)-monomorine I has been achieved, based on asymmetric nitrone cycloaddition using a chiral allyl ether.
