N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

Base Information

Chemical Name:N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide
CAS No.:338730-15-7
Molecular Formula:C₂₁H₂₈INO₇S
Molecular Weight:565.426
Hs Code.:

Synonyms:N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

Suppliers and Price of N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

There total 3 articles about N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 39964-89-1
N-(2'',2''-dimethoxyethyl)-4-methyl-N-(3''',4''',5'''-trimethoxyphenylmethyl)benzene sulfonamide

: 338730-15-7
N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

Guidance literature:: With iodine; silver trifluoroacetate; sodium hydrogencarbonate; In chloroform; at -10 - 0 ℃; for 3h;
DOI:10.1021/ja0101072

Reference yield:

: 21852-50-6
3,4,5-trimethoxybenzyl bromide

: 338730-15-7
N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide; various solvent(s) / 0.25 h

1.2: 97 percent / dimethylformamide / 3 h / 20 °C

2.1: 93 percent / I₂; CF₃CO₂Ag; sodium bicarbonate / CHCl₃ / 3 h / -10 - 0 °C

With iodine; silver trifluoroacetate; sodium hydride; sodium hydrogencarbonate; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/ja0101072

Reference yield:

: 58754-95-3
N-(2,2-dimethoxyethyl)-p-toluenesulfonamide

: 338730-15-7
N-(2,2-dimethoxyethyl)-N-[(2-iodo-3,4,5-trimethoxyphenyl)methyl]-p-toluenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide; various solvent(s) / 0.25 h

1.2: 97 percent / dimethylformamide / 3 h / 20 °C

2.1: 93 percent / I₂; CF₃CO₂Ag; sodium bicarbonate / CHCl₃ / 3 h / -10 - 0 °C

With iodine; silver trifluoroacetate; sodium hydride; sodium hydrogencarbonate; In chloroform; N,N-dimethyl-formamide;
DOI:10.1021/ja0101072