C₆₅H₇₂F₂O₁₀

Base Information

• Chemical Name: C₆₅H₇₂F₂O₁₀
• CAS No.: 1332755-94-8
• Molecular Formula: C₆₅H₇₂F₂O₁₀
• Molecular Weight: 1051.28
• Mol file: 1332755-94-8.mol

Synonyms:C₆₅H₇₂F₂O₁₀

Chemical Property of C₆₅H₇₂F₂O₁₀

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₅H₇₂F₂O₁₀

There total 19 articles about C₆₅H₇₂F₂O₁₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

4-((4'-hydroxybiphenyl-3-yloxy)carbonyl)phenyl-2,3-difluoro-4-(tetradecyloxy)benzoate + 4-((4-(undec-10-en-1-yloxy)benzoyl)oxy)benzoic acid (900525-42-0) → C65H72F2O10 (1332755-94-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1021/ja205550b

Reference yield:

4-(benzyloxycarbonyl)phenyl 4-tetradecyloxy-2,3-difluorobenzoate (1332755-86-8) → C65H72F2O10 (1332755-94-8)

Guidance literature:

Multi-step reaction with 4 steps

1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran

2: dmap; dicyclohexyl-carbodiimide / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / tetrahydrofuran

4: dmap; dicyclohexyl-carbodiimide / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere

With dmap; palladium 10% on activated carbon; hydrogen; dicyclohexyl-carbodiimide; In tetrahydrofuran;

DOI:10.1021/ja205550b

Reference yield:

p-benzyloxyphenylbromide (6793-92-6) → C65H72F2O10 (1332755-94-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C / Inert atmosphere

1.2: trialkyl borate / -78 - 20 °C / Inert atmosphere

1.3: Inert atmosphere

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / ethanol; toluene / 5 h / 80 °C / Inert atmosphere

3.1: dmap; dicyclohexyl-carbodiimide / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere

4.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran

5.1: dmap; dicyclohexyl-carbodiimide / tetrahydrofuran / 16 h / 20 °C / Inert atmosphere

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; palladium 10% on activated carbon; hydrogen; potassium carbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol; hexane; toluene;

DOI:10.1021/ja205550b

upstream raw materials:

4-((4-(undec-10-en-1-yloxy)benzoyl)oxy)benzoic acid

4-undec-10-enyloxybenzoic acid benzyl ester

4-(benzyloxycarbonyl)phenyl 4-tetradecyloxy-2,3-difluorobenzoate

p-benzyloxyphenylbromide

Downstream raw materials:

C₇₂H₉₄F₂O₁₂Si₃