3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

Base Information

Chemical Name:3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide
CAS No.:1352036-21-5
Molecular Formula:C₂₄H₂₁ClNO₂*I
Molecular Weight:517.794
Hs Code.:

Synonyms:3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

Suppliers and Price of 3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

There total 7 articles about 3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1352036-20-4
3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxyisoquinoline

: 74-88-4
methyl iodide

: 1352036-21-5
3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

Guidance literature:: at 100 ℃; sealed tube;

Reference yield:

: 2107-69-9
5,6-dimethoxy-1-indanone

: 1352036-21-5
3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

Guidance literature:: Multi-step reaction with 7 steps

1.1: hydrogenchloride; n-Butyl nitrite / water; methanol / 2.5 h / 40 °C

2.1: sodium hydroxide; p-toluenesulfonyl chloride / water / 0.25 h / 50 - 80 °C

2.2: pH 3 - 4

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C / Inert atmosphere

4.1: hydrogen bromide / diethyl ether / 2 h

5.1: potassium carbonate / palladium diacetate; XPhos / acetonitrile; water / 1.5 h / 100 °C

6.1: trichlorophosphate / 3 h / 110 °C

7.1: 100 °C / sealed tube

With hydrogenchloride; oxalyl dichloride; n-Butyl nitrite; hydrogen bromide; potassium carbonate; p-toluenesulfonyl chloride; sodium hydroxide; trichlorophosphate; palladium diacetate; N,N-dimethyl-formamide; XPhos; In methanol; diethyl ether; dichloromethane; water; acetonitrile;

Reference yield:

: 76254-26-7
2-(cyanomethyl)-4,5-dimethoxybenzoic acid

: 1352036-21-5
3-([1,1'-biphenyl]-3-yl)-1-chloro-6,7-dimethoxy-2-methylisoquinolin-2-ium iodide

Guidance literature:: Multi-step reaction with 5 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: hydrogen bromide / diethyl ether / 2 h

3: potassium carbonate / palladium diacetate; XPhos / acetonitrile; water / 1.5 h / 100 °C

4: trichlorophosphate / 3 h / 110 °C

5: 100 °C / sealed tube

With oxalyl dichloride; hydrogen bromide; potassium carbonate; trichlorophosphate; palladium diacetate; N,N-dimethyl-formamide; XPhos; In diethyl ether; dichloromethane; water; acetonitrile;