Technology Process of 4-Chloroacridine
There total 6 articles about 4-Chloroacridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
o-chloroaniline;
With
1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate;
In
toluene;
at 20 ℃;
for 0.0833333h;
Inert atmosphere;
ortho-bromobenzaldehyde;
In
toluene;
at 80 ℃;
for 12h;
Inert atmosphere;
With
aluminum (III) chloride;
In
toluene;
at 80 ℃;
for 12h;
DOI:10.1039/c5ob00755k
- Guidance literature:
-
With
1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate;
In
toluene;
at 20 ℃;
for 0.0833333h;
Inert atmosphere;
In
toluene;
at 80 ℃;
for 12h;
- Guidance literature:
-
With
trichloroacetonitrile; triphenylphosphine;
In
toluene;
at 115 ℃;
for 4h;
regioselective reaction;
Sealed tube;
DOI:10.1002/ejoc.201501567
