C₁₈H₂₀BrNO₂

Base Information

• Chemical Name: C₁₈H₂₀BrNO₂
• CAS No.: 1234560-10-1
• Molecular Formula: C₁₈H₂₀BrNO₂
• Molecular Weight: 362.266
• Mol file: 1234560-10-1.mol

Synonyms:C₁₈H₂₀BrNO₂

Chemical Property of C₁₈H₂₀BrNO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₀BrNO₂

There total 1 articles about C₁₈H₂₀BrNO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

di-tert-butyl dicarbonate (24424-99-5) + N-(2-bromobenzyl)benzenamine (50844-92-3) → C18H20BrNO2 (1234560-10-1)

Guidance literature:

With potassium hexamethylsilazane; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1055/s-0029-1219580

Reference yield:

C18H20BrNO2 (1234560-10-1) → phenanthridine (229-87-8) + N-Benzylaniline (758640-21-0,103-32-2)

Guidance literature:

C₁₈H₂₀BrNO₂; With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; potassium carbonate; In toluene; at 150 ℃; for 2h; Microwave irradiation;

With hydrogenchloride; water; In ethyl acetate; at 20 ℃; for 0.5h;

With oxygen;

DOI:10.1055/s-0029-1219580

Reference yield:

C18H20BrNO2 (1234560-10-1) → N-Boc-N-phenylbenzylamine (1307800-81-2) + tert-butyl phenanthridine-5(6H)-carboxylate (1234560-11-2)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; potassium carbonate; In toluene; at 150 ℃; for 2h; Microwave irradiation;

DOI:10.1055/s-0029-1219580

upstream raw materials:

di-tert-butyl dicarbonate

N-(2-bromobenzyl)benzenamine

Downstream raw materials:

phenanthridine

N-Benzylaniline

N-Boc-N-phenylbenzylamine

tert-butyl phenanthridine-5(6H)-carboxylate