1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

Base Information

Chemical Name:1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)
CAS No.:95676-27-0
Molecular Formula:C₂₄H₂₆N₂O₆
Molecular Weight:438.48
Hs Code.:

Synonyms:1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

Suppliers and Price of 1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

There total 4 articles about 1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.8%

: 51425-66-2
(4,5-dihydro-2-furanyloxy)(trimethyl)silane

: 95676-25-8
1,4-bis(p-methoxybenzyl)-3-(2'-thiopyridyl)-2,5-piperazinedione

: 95676-26-9
1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (major diastereomer)

: 95676-27-0
1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

Guidance literature:: With silver trifluoromethanesulfonate; In dichloromethane; for 0.5h; Ambient temperature;
DOI:10.1021/ja00297a034

Reference yield:

: 92097-99-9
1,4-bis(4-methoxybenzyl)piperazine-2,5-dione

: 95676-27-0
1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

Guidance literature:: Multi-step reaction with 3 steps

1: 66 percent / N-bromosuccinimide / benzoyl peroxide / CCl₄ / 1 h / Heating

2: 1.) NaH / 1.) THF, 30 min; 2.) THF, 25 deg C, 10 min

3: 18.8 percent / AgOTf / CH₂Cl₂ / 0.5 h / Ambient temperature

With N-Bromosuccinimide; silver trifluoromethanesulfonate; sodium hydride; dibenzoyl peroxide; In tetrachloromethane; dichloromethane;
DOI:10.1021/ja00297a034

Reference yield:

: 2746-25-0
p-Methoxybenzyl bromide

: 95676-27-0
1,4-bis(p-methoxybenzyl)-3-(2'-γ-butyrolactonyl)-2,5-piperazinedione (minor diastereomer)

Guidance literature:: Multi-step reaction with 4 steps

1: NaH / dimethylformamide / 25 °C

2: 66 percent / N-bromosuccinimide / benzoyl peroxide / CCl₄ / 1 h / Heating

3: 1.) NaH / 1.) THF, 30 min; 2.) THF, 25 deg C, 10 min

4: 18.8 percent / AgOTf / CH₂Cl₂ / 0.5 h / Ambient temperature

With N-Bromosuccinimide; silver trifluoromethanesulfonate; sodium hydride; dibenzoyl peroxide; In tetrachloromethane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja00297a034