1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

Base Information

Chemical Name:1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester
CAS No.:936727-37-6
Molecular Formula:C₁₉H₃₀O₄Si
Molecular Weight:350.53
Hs Code.:

Synonyms:1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

Suppliers and Price of 1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

There total 5 articles about 1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 936727-36-5
1-(3-hydroxymethyl-4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester

: 18162-48-6
tert-butyldimethylsilyl chloride

: 936727-37-6
1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

Guidance literature:: With 1H-imidazole; In dichloromethane; at 20 ℃;

Reference yield: 56.0%

: 288-32-4
1H-imidazole

: 936727-36-5
1-(3-hydroxymethyl-4-methoxyphenyl)cyclopropanecarboxylic acid methyl ester

: TBSCl

: 936727-37-6
1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

Guidance literature:: In dichloromethane;

Reference yield:

: 16728-01-1
1-(4-methoxyphenyl)-1-cyclopropanecarboxylic acid

: 936727-37-6
1-[3-(tert-butyl-dimethyl-silanyloxymethyl)-4-methoxyphenyl]cyclopropane carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: toluene-4-sulfonic acid / 20 h / Reflux

2: titanium tetrachloride / carbon disulfide / 24 h / 5 - 30 °C

3: tetrabutylammomium bromide; sodium carbonate / water / 65 °C

4: 1H-imidazole / dichloromethane / 20 °C

With 1H-imidazole; tetrabutylammomium bromide; titanium tetrachloride; sodium carbonate; toluene-4-sulfonic acid; In carbon disulfide; dichloromethane; water;