4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

Base Information

Chemical Name:4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal
CAS No.:1590392-14-5
Molecular Formula:C₄₉H₆₂O₁₃
Molecular Weight:859.023
Hs Code.:

Synonyms:4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

Suppliers and Price of 4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

There total 8 articles about 4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1590392-13-4
4-O-(3,6-di-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

: 100-39-0
benzyl bromide

: 1590392-14-5
4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

Guidance literature:: 4-O-(3,6-di-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.5h;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 12h;
DOI:10.1016/j.carres.2014.01.020

Reference yield:

: 1590392-10-1
4-O-(6-O-benzyl-3,4-O-isopropylidene-2-O-p-methoxybenzyl-β-D-talopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

: 1590392-14-5
4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium tert-butylate / tetrahydrofuran / 0.33 h / Reflux

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil; hexane / 0.33 h / 0 - 20 °C

2.2: 12 h / 0 - 20 °C

3.1: dimethylsulfide borane complex / tetrahydrofuran; diethyl ether / 5 h / 0 - 20 °C / Inert atmosphere

3.2: 2 h / 0 - 20 °C / Inert atmosphere

4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C

4.2: 12 h / 0 - 20 °C

With dimethylsulfide borane complex; potassium tert-butylate; sodium hydride; In tetrahydrofuran; diethyl ether; hexane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.carres.2014.01.020

Reference yield:

: 1590392-11-2
4-O-(3,6-di-O-benzyl-4-deoxy-2-O-p-methoxybenzyl-β-D-erhytrohex-4-enopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

: 1590392-14-5
4-O-(3,4,6-tri-O-benzyl-2-O-p-methoxybenzyl-β-D-mannopyranosyl)-2,3:5,6-di-O-isopropylidenealdehydo-D-glucose dimethyl acetal

Guidance literature:: Multi-step reaction with 2 steps

1.1: dimethylsulfide borane complex / tetrahydrofuran; diethyl ether / 5 h / 0 - 20 °C / Inert atmosphere

1.2: 2 h / 0 - 20 °C / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C

2.2: 12 h / 0 - 20 °C

With dimethylsulfide borane complex; sodium hydride; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.carres.2014.01.020