C₄₀H₅₄O₉Si

Base Information

• Chemical Name: C₄₀H₅₄O₉Si
• CAS No.: 512780-87-9
• Molecular Formula: C₄₀H₅₄O₉Si
• Molecular Weight: 706.949
• Mol file: 512780-87-9.mol

Synonyms:C₄₀H₅₄O₉Si

Chemical Property of C₄₀H₅₄O₉Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₀H₅₄O₉Si

There total 7 articles about C₄₀H₅₄O₉Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

C40H54O9Si (512828-46-5) → C40H54O9Si (512780-87-9)

Guidance literature:

With aluminum isopropoxide; In benzene; at 50 ℃; for 24h;

DOI:10.1021/jo020628n

Reference yield:

benzoyl chloride (98-88-4) → C40H54O9Si (512780-87-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / Et₃N; DMAP / CH₂Cl₂ / 12 h

2: 77 percent / aluminum isopropoxide / benzene / 24 h / 50 °C

With dmap; aluminum isopropoxide; triethylamine; In dichloromethane; benzene;

DOI:10.1021/jo020628n

Reference yield:

(1S,2R,4S,5S,9R,11S,12S)-5-(tert-Butyl-dimethyl-silanyloxy)-11,12-dihydroxy-2-(4-methoxy-benzyloxy)-4,15,15-trimethyl-8-methylene-tricyclo[10.2.1.04,9]pentadecan-3-one (350715-45-6) → C40H54O9Si (512780-87-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 100 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / 5.5 h / -78 - 20 °C

2.1: potassium tert-butoxide / dimethylformamide / 0.5 h / 0 °C

2.2: 89 percent / dimethylformamide / 0.5 h / 0 °C

3.1: 80 percent / m-CPBA; NaHCO₃ / CH₂Cl₂ / 36 h / 0 °C

4.1: 95 percent / camphorsulfonic acid / CH₂Cl₂ / 24 h / 20 °C

5.1: 94 percent / Et₃N; DMAP / CH₂Cl₂ / 12 h

6.1: 77 percent / aluminum isopropoxide / benzene / 24 h / 50 °C

With dmap; oxalyl dichloride; camphor-10-sulfonic acid; potassium tert-butylate; aluminum isopropoxide; sodium hydrogencarbonate; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide; benzene; 1.1: Swern oxidation;

DOI:10.1021/jo020628n

upstream raw materials:

C₄₀H₅₄O₉Si

benzoyl chloride

(1S,2R,4S,5S,9R,11S,12S)-5-(tert-Butyl-dimethyl-silanyloxy)-11,12-dihydroxy-2-(4-methoxy-benzyloxy)-4,15,15-trimethyl-8-methylene-tricyclo[10.2.1.0^4,9]pentadecan-3-one

(1S,4R,8S,9S,11R,12S)-8-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-11-(4-methoxy-benzyloxy)-9,15,15-trimethyl-5-methylene-tricyclo[10.2.1.0^4,9]pentadecane-2,10-dione

Downstream raw materials:

Benzoic acid (1S,2S,3R,7S,8S,10R,11S)-7-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-10-(4-methoxy-benzyloxy)-8,15,15-trimethyl-9,14-dioxo-4-trimethylsilanyloxymethyl-tricyclo[9.3.1.0^3,8]pentadec-4-en-2-yl ester

Benzoic acid (1S,2S,3R,7S,8S,10R,11S)-7-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4-hydroxymethyl-10-(4-methoxy-benzyloxy)-8,15,15-trimethyl-9,14-dioxo-tricyclo[9.3.1.0^3,8]pentadec-4-en-2-yl ester

Benzoic acid (1S,2S,3R,5S,7S,8S,10R,11S)-7-(tert-butyl-dimethyl-silanyloxy)-1,5-dihydroxy-10-(4-methoxy-benzyloxy)-8,15,15-trimethyl-4-methylene-9,14-dioxo-tricyclo[9.3.1.0^3,8]pentadec-2-yl ester

C₄₀H₅₄O₁₀Si