2-[3-(4-Chlorophenyl)-5-methoxyphenyl]acetic acid

Base Information

Chemical Name:2-[3-(4-Chlorophenyl)-5-methoxyphenyl]acetic acid
CAS No.:51028-89-8
Molecular Formula:C₁₅H₁₃ClO₃
Molecular Weight:276.719
Hs Code.:2922299090
DSSTox Substance ID:DTXSID50199034
Nikkaji Number:J22.700E
Wikidata:Q83071920
ChEMBL ID:CHEMBL6937
Mol file:51028-89-8.mol

Synonyms:3-methoxy-5-(p-chlorophenyl)phenylacetic acid;4'-chloro-5-methoxy-3-biphenylacetic acid;DKA 9;DKA-9

Suppliers and Price of 2-[3-(4-Chlorophenyl)-5-methoxyphenyl]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4'-CHLORO-5-METHOXY-BIPHENYL-3-ACETIC ACID 95.00%
5MG
$ 496.57

Total 0 raw suppliers

Chemical Property of 2-[3-(4-Chlorophenyl)-5-methoxyphenyl]acetic acid

Chemical Property:

Boiling Point:437.2°Cat760mmHg
Flash Point:218.2°C
PSA：46.53000
Density:1.268g/cm³
LogP:3.64270
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:276.0553220
Heavy Atom Count:19
Complexity:300

Purity/Quality:: 4'-CHLORO-5-METHOXY-BIPHENYL-3-ACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=CC(=C1)C2=CC=C(C=C2)Cl)CC(=O)O

Technology Process of 2-[3-(4-Chlorophenyl)-5-methoxyphenyl]acetic acid

There total 7 articles about 2-[3-(4-Chlorophenyl)-5-methoxyphenyl]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 53183-84-9
(4'-Chloro-5-methoxy-biphenyl-3-yl)-acetic acid methyl ester

: 51028-89-8
4'-chloro-5-methoxy-3-biphenylylacetic acid

Guidance literature:: With sodium hydroxide; In methanol;
DOI:10.1021/jm00215a018

Reference yield:

: 3160-40-5
4-(4-chlorophenyl)-3-buten-2-one

: 51028-89-8
4'-chloro-5-methoxy-3-biphenylylacetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: (i) NaOMe, MeOH, (ii) aq. NaOH, (iii) aq. HCl

2: POCl₃, Na₂CO₃ / toluene

3: Na / toluene

4: Br₂ / benzene

5: aq. NaOH / methanol

With sodium hydroxide; bromine; sodium; sodium carbonate; trichlorophosphate; In methanol; toluene; benzene;
DOI:10.1021/jm00215a018

Reference yield:

: 27463-38-3
5-(4-chlorophenyl)cyclohexane-1,3-dione

: 51028-89-8
4'-chloro-5-methoxy-3-biphenylylacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: POCl₃, Na₂CO₃ / toluene

2: Na / toluene

3: Br₂ / benzene

4: aq. NaOH / methanol

With sodium hydroxide; bromine; sodium; sodium carbonate; trichlorophosphate; In methanol; toluene; benzene;
DOI:10.1021/jm00215a018