[C₅H₄CONHCH₂CH(C₆H₅)OH]2Fe

Base Information

• Chemical Name: [C₅H₄CONHCH₂CH(C₆H₅)OH]2Fe
• CAS No.: 877175-53-6
• Molecular Formula: C₂₈H₂₈FeN₂O₄
• Molecular Weight: 512.388
• Mol file: 877175-53-6.mol

Synonyms:[C₅H₄CONHCH₂CH(C₆H₅)OH]2Fe

Chemical Property of [C₅H₄CONHCH₂CH(C₆H₅)OH]2Fe

Chemical Property:

Purity/Quality:

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Technology Process of [C₅H₄CONHCH₂CH(C₆H₅)OH]2Fe

There total 1 articles about [C₅H₄CONHCH₂CH(C₆H₅)OH]2Fe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1,1'-ferrocenyldicarbonyl chloride (1273-94-5) + 2-Amino-1-phenylethanol (7568-93-6,1936-63-6) → [C5H4CONHCH2CH(C6H5)OH]2Fe (877175-53-6)

Guidance literature:

With Et₃N; In dichloromethane; (Ar), ferrocenyl in CH2Cl2 slowly added at 0°C to ligand and Et3Nin CH2Cl2, stirred for 4 h; Washed (sat. soln. of NaHCO3, brine), org. phase dried (Na2SO4), evapd.(vac.), chromy.(silica gel - ethyl acetate/n-hexane), elem. anal.;

DOI:10.1002/ejic.200400737

Reference yield: 76.0%

[C5H4CONHCH2CH(C6H5)OH]2Fe (877175-53-6) → 1,1'-bis[5-phenyloxazolin-2-yl]ferrocene (877175-67-2)

Guidance literature:

With p-toluenesulfonyl chloride; triethylamine; catalyst: 4-(dimethylamino)pyridine; In dichloromethane; (Ar), soln. of p-toluenesulfonyl chloride in CH2Cl2 added dropwise at 0°C to soln. of Fe complex, Et3N and catalyst: 4-(dimethylamino)pyridine in CH2Cl2, stirred at room temp. for 10 h; washed *sat. soln. of NaHCO3, brine), water layer extd.(CH2Cl2), org. phase dried (Na2SO4), chromy.(silica gel - ethyl acetate/n-hexane), elem. anal.;

DOI:10.1002/ejic.200400737

upstream raw materials:

1,1'-ferrocenyldicarbonyl chloride

2-Amino-1-phenylethanol

Downstream raw materials:

1,1'-bis[5-phenyloxazolin-2-yl]ferrocene