4,4'-bis(azidomethyl)diphenylmethane

Base Information

• Chemical Name: 4,4'-bis(azidomethyl)diphenylmethane
• CAS No.: 199920-10-0
• Molecular Formula: C₁₅H₁₄N₆
• Molecular Weight: 278.316
• Mol file: 199920-10-0.mol

Synonyms:4,4'-bis(azidomethyl)diphenylmethane

Chemical Property of 4,4'-bis(azidomethyl)diphenylmethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-bis(azidomethyl)diphenylmethane

There total 1 articles about 4,4'-bis(azidomethyl)diphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

bis(4-bromomethylphenyl)methane (16980-01-1) → 4,4'-bis(azidomethyl)diphenylmethane (199920-10-0)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 60 ℃; for 10h;

DOI:10.1021/ja051685b

Reference yield: 87.0%

4,4'-bis(azidomethyl)diphenylmethane (199920-10-0) → 4,4'-di-(aminomethyl)-diphenylmethane (4934-35-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Heating;

DOI:10.1021/jm970571a

Reference yield:

4-O-propargyl-2-deoxystreptamine + 4,4'-bis(azidomethyl)diphenylmethane (199920-10-0) → C33H46N10O6

Guidance literature:

With tetrakis(actonitrile)copper(I) hexafluorophosphate; In dimethyl sulfoxide; for 0.0111111h; microwave irradiation;

DOI:10.1021/ja051685b

upstream raw materials:

bis(4-bromomethylphenyl)methane

Downstream raw materials:

4,4'-di-(aminomethyl)-diphenylmethane

Refernces

• 1、 Rosa, Joaquin Campos,Galanakis, Dimitrios,Piergentili, Alessandro,Bhandari, Kalpana,Ganellin, C. Robin,Dunn, Philip M.,Jenkinson, Donald H.. "Synthesis, molecular modeling, and pharmacological testing of bis- quinolinium cyclophanes: Potent, non-peptidic blockers of the apamin- sensitive Ca2+-activated K+ channel". . p. 420 - 431. Retrieved 2000.