16980-01-1

Upstream product

• 50-00-0 formaldehyd 
• 101-81-5 Diphenylmethane 
• 4957-14-6 4,4'-dimethyldiphenylmethane 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 1515-88-4 1-bromo-4-methoxymethylbenzene 
• 90021-26-4 4,4'-Bis-methoxymethyl benzophenone 

Downstream Products

• 140149-19-5 Bis<4-(4-methyl>phenoxymethyl)phenyl>methan 
• 153897-24-6 C₅₂H₄₄O₁₀ 
• 142421-21-4 (Methandiyl-4,4'-dibenzyl)bis(triphenylphosphoniumbromid) 
• 203246-31-5 {4-[4-(Dimethoxy-phosphorylmethyl)-benzyl]-benzyl}-phosphonic acid dimethyl ester 
• 253877-87-1 N₁-{6-[(mesitylsulfonyl)(4-{4-[((mesitylsulfonyl){6-[(mesitylsulfonyl)(2-methoxybenzyl)amino]hexyl}amino)methyl]benzyl}benzyl)amino]hexyl}-N₁-(2-methoxybenzyl)-2,4,6-trimethyl-1-benzenesulfonamide 
• 1049710-94-2 CH₂(C₆H₄CH₂OC₆H₃(OH)CHO)2 

Relevant academic research and scientific papers

MOLECULAR ANION BINDING AND SUBSTRATE PHOTOXIDATION IN VISIBLE LIGHT BY 2,7-DIAZEPYRENIUM CATIONS

The 2,7-diazapyrenium group (DAP 2+) combines the features of pyrne, of methylviologen, and of nucleic acid intercalators and may thus present a variety of interesting properties.The cation 1 and 2 and the bis-diazapyrenium species 3 have been

Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes

A series of 73 bisphosphonium salts and 10 monophosphonium salt derivatives were synthesized and tested in vitro against several wild type and resistant lines of Trypanosoma brucei (T. b. rhodesiense STIB900, T. b. brucei strain 427, TbAT1-KO, and TbB48). More than half of the compounds tested showed a submicromolar EC50 against these parasites. The compounds did not display any cross-resistance to existing diamidine therapies, such as pentamidine. In most cases, the compounds displayed a good selectivity index versus human cell lines. None of the known T. b. brucei drug transporters were required for trypanocidal activity, although some of the bisphosphonium compounds inhibited the low affinity pentamidine transporter. It was found that phosphonium drugs act slowly to clear a trypanosome population but that only a short exposure time is needed for irreversible damage to the cells. A comparative molecular field analysis model (CoMFA) was generated to gain insights into the SAR of this class of compounds, identifying key features for trypanocidal activity.

Multiple weak supramolecular interactions stabilize a surprisingly twisted As2L3 assembly

A combined crystallographic, DFT and NMR spectroscopic study of a flexible As2L3 assembly reveals temperature dependent conformational behavior in solution and a highly asymmetric structure stabilized by As-π and edge-to-face aromati

Conformational interconversions in [2]catenanes containing a wide rigid bis(p-benzyl)methyl spacer

(Figure Presented) The conformational interconversions of four [2]catenanes (1-4) containing a dibenzo-34-crown-10 ether (BPP34C10) interlocked with rings containing two 4,4′-dipyridiniums tethered by 1,3-bis(ethyloxy)-phenyl and bis(p-benzyl)methyl spacers have been studied by VT 1H NMR spectroscopy. Symmetrically placed blocking groups on thickened tethers enabled either pathway for circumrotation of the BPP34C10 between isoenergetic sites to be blocked. On the basis of chemical shifts of the BPP34C10, its internal p-hydroquinone forms π-π-stacking interactions with only one 4,4′-dipyridinium ring at a time. The activation barrier for migration along either open tether was approximately 11.5 kcal/mol. This study demonstrates an ability to select the pathway for conformational interconversions in these [2]catenanes containing the rigid bis(p-benzyl)methyl tether and the lowering the barrier for interconversion through destabilization of the ground state structures.

Synthetic protocols and building blocks for molecular electronics

Simple and readily accessible aryl bromides are useful building blocks for thiol end-capped molecular wires. Thus, 4-bromophenyl tert-butyl sulfide and 1-bromo-4-(methoxymethyl)benzene serve as precursors for a variety of oligo(phenylenevinylene) and olig

Efficient light harvesting by sequential energy transfer across aggregates in polymers of finite conjugational segments with short aliphatic linkages

Interactions between lumophores have a critical influence on the photophysical properties of conjugated polymers. We synthesized a new series of light-harvesting polymers (poly-DSBs, I-IV) of dialkyloxy- or dialkyl- substituted distyrylbenzene (the substituents being methoxy, 2-ethylhexyloxy, and cyclohexyl) with short aliphatic linkage (methylene or ethylene) and examined the effects of interactions between lumophores and of chemical structures on the absorption, emission, and excitation spectra. The proximity between distyrylbenzene lumophores was shown to be critical to the interactions between lumophores and to the energy-transfer processes. In concentrated solutions and solid films, intermolecular aggregates exist resulting from different extents of interactions between lumophores and are found to involve at least three species: loose, compact, and the most aligned aggregates as observed by photoluminescence and excitation spectroscopies. We also found, for the first time, sequential energy transfer from individual lumophores to the most compact, aligned aggregates via the looser intermolecular aggregates, as observed directly by time-resolved fluorescence spectroscopy. Such a process mimics energy transfer in photosynthesis units and is so efficient such that the fluorescence color can be red-shifted drastically by the presence of comparatively few aggregates and that the light evolved from concentrated solutions and films of poly-DSBs I-IV is entirely or almost the aggregation emission. Although the sequential energy-transfer process in fully conjugated electro-/photoluminescent polymers due to inhomogenity other than distributed conjugation lengths has never been directly observed at room temperature, we suggest that events similar to those observed in poly-DSBs in conjugated polymers could occur but on a much shorter time scale, i.e., a few picoseconds.