1,3-diphenylprop-2-yn-1-yl acetate

Base Information

• Chemical Name: 1,3-diphenylprop-2-yn-1-yl acetate
• CAS No.: 93321-44-9
• Molecular Formula: C₁₇H₁₄O₂
• Molecular Weight: 250.297
• Mol file: 93321-44-9.mol

Synonyms:1,3-diphenylprop-2-yn-1-yl acetate

Chemical Property of 1,3-diphenylprop-2-yn-1-yl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-diphenylprop-2-yn-1-yl acetate

There total 12 articles about 1,3-diphenylprop-2-yn-1-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,3-diphenyl-1-propyn-3-ol (1817-49-8) + acetic anhydride (108-24-7) → 1,3-diphenylprop-2-yn-1-yl acetate (93321-44-9)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1002/cjoc.201400396

Reference yield: 95.0%

1,3-diphenyl-1-propyn-3-ol (1817-49-8) + acetyl chloride (75-36-5) → 1,3-diphenylprop-2-yn-1-yl acetate (93321-44-9)

Guidance literature:

With pyridine; dmap; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/ja062777j

Reference yield: 93.0%

acetic anhydride (108-24-7) + benzaldehyde (100-52-7) + phenylacetylene (536-74-3) → 1,3-diphenylprop-2-yn-1-yl acetate (93321-44-9)

Guidance literature:

phenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h; Inert atmosphere;

benzaldehyde; In tetrahydrofuran; hexane; at -78 - 0 ℃; Inert atmosphere;

acetic anhydride; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1055/s-0030-1258992

upstream raw materials:

1,3-diphenyl-1-propyn-3-ol

acetic anhydride

acetyl chloride

benzaldehyde

Downstream raw materials:

N-(1,3-diphenyl-prop-2-ynyl)-benzamide

(Z)-2-benzylidene-1-phenylbutane-1,3-dione

1-Phenyl-2-[1-phenyl-meth-(E)-ylidene]-butane-1,3-dione

(E)-2-iodo-1,3-diphenyl-n-prop-2-en-1-one

Refernces

• 1、 Jiang, Quanbin,Li, Huimin,Zhao, Xiaodan. "Catalytic Electrophilic Thiocarbocyclization of Allenes". supporting information. p. 8777 - 8782. Retrieved 2021/11/17.
• 2、 Shao, Xue Bei,Zhang, Zhen,Li, Qing Han,Zhao, Zhi Gang. "Synthesis of multi-substituted allenes from organoalane reagents and propargyl esters by using a nickel catalyst". . p. 4797 - 4806. Retrieved 2018/07/13.