Technology Process of C25H31ClO8
There total 7 articles about C25H31ClO8 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: triethylsilane; trifluorormethanesulfonic acid; trifluoroacetic acid / 20 °C / Reflux
2.1: boron tribromide / dichloromethane / -78 - 20 °C
3.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C
3.2: 80 °C
4.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C
4.2: 0 - 20 °C
5.1: n-butyllithium / tetrahydrofuran; toluene / -78 °C / Inert atmosphere
5.2: 1 h / -78 °C
With
triethylsilane; n-butyllithium; trifluorormethanesulfonic acid; boron tribromide; sodium hydride; caesium carbonate; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
2-(4-(2-(allyloxy)ethoxy)benzyl)-4-bromo-1-chlorobenzene;
With
n-butyllithium;
In
tetrahydrofuran; toluene;
at -78 ℃;
Inert atmosphere;
(3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one;
In
tetrahydrofuran; toluene;
at -78 ℃;
for 1h;
methanol;
With
methanesulfonic acid;
In
tetrahydrofuran; toluene;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 20 °C
2.1: aluminum (III) chloride / dichloromethane / -5 - 4 °C
3.1: triethylsilane; trifluorormethanesulfonic acid; trifluoroacetic acid / 20 °C / Reflux
4.1: boron tribromide / dichloromethane / -78 - 20 °C
5.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C
5.2: 80 °C
6.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C
6.2: 0 - 20 °C
7.1: n-butyllithium / tetrahydrofuran; toluene / -78 °C / Inert atmosphere
7.2: 1 h / -78 °C
With
triethylsilane; aluminum (III) chloride; n-butyllithium; oxalyl dichloride; trifluorormethanesulfonic acid; boron tribromide; sodium hydride; caesium carbonate; trifluoroacetic acid;
N,N-dimethyl-formamide;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
