Dynorphin (1-11)

Base Information Edit

Chemical Name:Dynorphin (1-11)
CAS No.:79985-34-5
Molecular Formula:C₆₃H₁₀₃N₂₁O₁₃
Molecular Weight:1362.64
Hs Code.:
DSSTox Substance ID:DTXSID20229978
Nikkaji Number:J535.859K
ChEMBL ID:CHEMBL438223
Mol file:79985-34-5.mol

Synonyms:dynorphin (1-11)

Suppliers and Price of Dynorphin (1-11)

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Dynorphin (1-11) Edit

Chemical Property:

PSA：577.48000
Density:1.42g/cm³
LogP:4.64670
XLogP3:-4.7
Hydrogen Bond Donor Count:19
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:44
Exact Mass:1361.80442243
Heavy Atom Count:97
Complexity:2640

Purity/Quality:: 80%，90%，95%，98%，99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N
Isomeric SMILES:CC[C@H](C)[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)[C@H](CC3=CC=C(C=C3)O)N

Technology Process of Dynorphin (1-11)

There total 3 articles about Dynorphin (1-11) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₀H₂₉N₂O₆Pol

: 29022-11-5
N-(fluoren-9-ylmethoxycarbonyl)glycine

: 35661-60-0
Fmoc-Leu-OH

: 71989-31-6
Fmoc-Pro-OH

: 35661-40-6
N-Fmoc L-Phe

: 71989-23-6,251316-98-0
Fmoc-Ile-OH

: 71989-38-3,118488-18-9,204384-67-8
Fmoc-Tyr(tBu)-OH

: 187618-60-6
Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine

: 79985-34-5
dynorphin(1-11)

Guidance literature:: C₂₀H₂₉N₂O₆Pol; Fmoc-Pro-OH; With 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In dichloromethane; N,N-dimethyl-formamide; for 2h; solid phase reaction;

With piperidine; In N,N-dimethyl-formamide; for 0.333333h; solid phase reaction;

N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Leu-OH; N-Fmoc L-Phe; Fmoc-Ile-OH; Fmoc-Tyr(tBu)-OH; Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine; Further stages;
DOI:10.1021/jm900715m