1-(3,5-Diacetoxyphenyl)-1-bromoethane

Base Information

• Chemical Name: 1-(3,5-Diacetoxyphenyl)-1-bromoethane
• CAS No.: 1026420-83-6
• Molecular Formula: C₁₂H₁₃BrO₄
• Molecular Weight: 301.137
• Mol file: 1026420-83-6.mol

Synonyms:1-(1-bromoethyl)-3,5-diacetoxybenzene

Chemical Property of 1-(3,5-Diacetoxyphenyl)-1-bromoethane

Chemical Property:

• Solubility.: Dichloromethane, Methanol

Purity/Quality:

97% ^*data from raw suppliers

1-(3,5-Diacetoxyphenyl)-1-bromoethane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate for the synthesis of Resveratrol.

Technology Process of 1-(3,5-Diacetoxyphenyl)-1-bromoethane

There total 1 articles about 1-(3,5-Diacetoxyphenyl)-1-bromoethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(1-hydroxyethyl)-3,5-diacetoxybenzene (847862-83-3) → 1-(1-bromoethyl)-3,5-diacetoxybenzene (1026420-83-6)

Guidance literature:

With phosphorus tribromide; In DMF (N,N-dimethyl-formamide); dichloromethane; at 0 ℃; for 3h;

Reference yield: 77.0%

1-(1-bromoethyl)-3,5-diacetoxybenzene (1026420-83-6) + 4-bromophenyl acetate (1927-95-3) → (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol (501-36-0)

Guidance literature:

1-(1-bromoethyl)-3,5-diacetoxybenzene; With lithium carbonate; In ISOPROPYLAMIDE; at 120 ℃; for 2h; Inert atmosphere;

4-bromophenyl acetate; With potassium phosphate; palladium oximate; In ISOPROPYLAMIDE; at 130 ℃; for 19.75h; Inert atmosphere;

With water; potassium carbonate; at 110 ℃; for 2.5h; Product distribution / selectivity;

Reference yield: 56.0%

1-(1-bromoethyl)-3,5-diacetoxybenzene (1026420-83-6) → 3-vinylphenyl acetate (2454-30-0) + 5-vinyl-1,3-phenylene diacetate (155222-48-3)

Guidance literature:

With lithium carbonate; lithium bromide; In DMF (N,N-dimethyl-formamide); at 120 ℃; for 18h; Product distribution / selectivity;

upstream raw materials:

1-(1-hydroxyethyl)-3,5-diacetoxybenzene

Downstream raw materials:

3-vinylphenyl acetate

5-vinyl-1,3-phenylene diacetate

(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

resveratrol

Refernces