N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate

Base Information

Chemical Name:N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate
CAS No.:1607465-09-7
Molecular Formula:C₂HF₃O₂*C₁₇H₂₂N₄O₂S
Molecular Weight:460.477
Hs Code.:

Synonyms:N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate

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Chemical Property of N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate

Chemical Property:

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Technology Process of N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate

There total 3 articles about N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1607465-03-1
N-tert-butoxycarbonyl[N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)]-6-aminohexanamide

: 76-05-1
trifluoroacetic acid

: 1607465-09-7
N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 24h;
DOI:10.1002/chem.201303664

Reference yield:

: 6404-29-1
6-(tert-butoxycarbonylamino)hexanoic acid

: 1607465-09-7
N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 2-chloro-1-methyl-pyridinium iodide; triethylamine / dichloromethane / 3 h / Reflux

2: dichloromethane / 24 h / 20 °C

With 2-chloro-1-methyl-pyridinium iodide; triethylamine; In dichloromethane;
DOI:10.1002/chem.201303664

Reference yield:

: 134812-30-9
N-(4-(3'-aminophenyl)thiazol-2-yl)acetamide

: 1607465-09-7
N-(2-N-acetylamino-4-(3-aminophenyl)thiazole)-6-aminohexanamide trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 2-chloro-1-methyl-pyridinium iodide; triethylamine / dichloromethane / 3 h / Reflux

2: dichloromethane / 24 h / 20 °C

With 2-chloro-1-methyl-pyridinium iodide; triethylamine; In dichloromethane;
DOI:10.1002/chem.201303664