5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

Base Information

Chemical Name:5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole
CAS No.:1346262-77-8
Molecular Formula:C₂₄H₁₆N₄O₃
Molecular Weight:408.416
Hs Code.:

Synonyms:5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

Suppliers and Price of 5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

There total 6 articles about 5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1346262-69-8
C₁₇H₁₂N₂

: 66912-26-3
o-nitrobenzonitrile N-oxide

: 1346262-77-8
5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

Guidance literature:: C₁₇H₁₂N₂; With triethylamine; 1,3-di-tert-butyl-1H-imidazol-3-ium chloride; In dichloromethane; at 0 - 5 ℃; for 0.166667h; Inert atmosphere;

o-nitrobenzonitrile N-oxide; In dichloromethane; at 0 - 20 ℃; for 0.666667h; regioselective reaction; Inert atmosphere;
DOI:10.1039/c1ob06072d

Reference yield:

: 19609-85-9
C₁₄H₁₀N₂

: 1346262-77-8
5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 4 h / Reflux

2.1: triethylamine; 1,3-di-tert-butyl-1H-imidazol-3-ium chloride / dichloromethane / 0.17 h / 0 - 5 °C / Inert atmosphere

2.2: 0.67 h / 0 - 20 °C / Inert atmosphere

With sodium hydride; triethylamine; 1,3-di-tert-butyl-1H-imidazol-3-ium chloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c1ob06072d

Reference yield:

: 35447-75-7
N-hydroxy-2-nitrobenzimidoyl chloride

: 1346262-77-8
5-(3-(2-nitrophenyl)-isoxazol-5-ylmethyl)-5H-benzo(4,5)imidazo(2,1-a)isoindole

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 0.03 h / 0 - 5 °C

2.1: triethylamine; 1,3-di-tert-butyl-1H-imidazol-3-ium chloride / dichloromethane / 0.17 h / 0 - 5 °C / Inert atmosphere

2.2: 0.67 h / 0 - 20 °C / Inert atmosphere

With triethylamine; 1,3-di-tert-butyl-1H-imidazol-3-ium chloride; In dichloromethane;
DOI:10.1039/c1ob06072d