Imiloxan

Base Information

Chemical Name:Imiloxan
CAS No.:81167-16-0
Molecular Formula:C₁₄H₁₆N₂O₂
Molecular Weight:244.293
Hs Code.:
UNII:ZJ56PS1DWK
DSSTox Substance ID:DTXSID1045162
Nikkaji Number:J23.742F
Wikipedia:Imiloxan
Wikidata:Q6004076
NCI Thesaurus Code:C83792
Pharos Ligand ID:FTRPRW1WUYZR
ChEMBL ID:CHEMBL347695
Mol file:81167-16-0.mol

Synonyms:Imiloxan

Suppliers and Price of Imiloxan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Tocris
Imiloxanhydrochloride ≥98%(HPLC)
50
$ 564.00

Tocris
Imiloxanhydrochloride ≥98%(HPLC)
10
$ 150.00

DC Chemicals
Imiloxan >98%
1 g
$ 1200.00

Biorbyt Ltd
Imiloxan >98%
250 mg
$ 912.90

Biorbyt Ltd
Imiloxan >98%
1000 mg
$ 1802.00

Biorbyt Ltd
Imiloxan >98%
100 mg
$ 606.90

American Custom Chemicals Corporation
IMILOXAN 95.00%
50MG
$ 1012.65

American Custom Chemicals Corporation
IMILOXAN 95.00%
10MG
$ 653.68

Total 10 raw suppliers

Chemical Property of Imiloxan

Chemical Property:

Vapor Pressure:1.31E-06mmHg at 25°C
Melting Point:170 - 172°C
Boiling Point:411.7°Cat760mmHg
PKA:7.24±0.31(Predicted)
Flash Point:202.8°C
PSA：36.28000
Density:1.22g/cm³
LogP:3.08750
Storage Temp.:Desiccate at RT
Solubility.:H2O: 30 mg/mL, soluble
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:244.121177757
Heavy Atom Count:18
Complexity:275

Purity/Quality:

99% ^*data from raw suppliers

Imiloxanhydrochloride ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=CN=C1CC2COC3=CC=CC=C3O2
Uses Antidepressant. Imiloxan Hydrochloride is an α2-?adrenoceptor antagonist.

Technology Process of Imiloxan

There total 4 articles about Imiloxan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18505-91-4
2-(2,3-Dihydro-1,4-benzodioxin-2-yl)acetonitrile

: 81167-16-0
imiloxan

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / HCl gas / 96 h / 5 °C

2: 2.) 4 N HCl / 1.) reflux, 18 h, 2.) 60 deg C, 24 h

3: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF, RT, 30 min

With hydrogenchloride; sodium hydride;
DOI:10.1021/jm00348a012

Reference yield:

: 3789-55-7
ethyl (1,4-benzodioxan-2-yl)acetimidate hydrochloride

: 81167-16-0
imiloxan

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) 4 N HCl / 1.) reflux, 18 h, 2.) 60 deg C, 24 h

2: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF, RT, 30 min

With hydrogenchloride; sodium hydride;
DOI:10.1021/jm00348a012