2-(p-Tolylthio)acetamide

Base Information

• Chemical Name: 2-(p-Tolylthio)acetamide
• CAS No.: 73623-29-7
• Molecular Formula: C9H11NOS
• Molecular Weight: 181.258
• Mol file: 73623-29-7.mol

Synonyms:p-Tolylmercapto-essigsaeure-amid;p-tolylsulfanyl-acetic acid amide;ACETAMIDE,2-(p-TOLYLTHIO);2-[(4-methylphenyl)sulfanyl]acetamide;C-p-Tolylmercapto-acetamid;

Chemical Property of 2-(p-Tolylthio)acetamide

Chemical Property:

• Vapor Pressure: 5.67E-05mmHg at 25°C
• Boiling Point: 346.7°Cat760mmHg
• Flash Point: 163.5°C
• PSA: 69.38000
• Density: 1.17g/cm³
• LogP: 2.72210

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(p-Tolylthio)acetamide

There total 3 articles about 2-(p-Tolylthio)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(p-tolylthio)acetic acid chloride (30893-63-1) → 2-(4-methylphenylsulfanyl)acetamide (73623-29-7)

Guidance literature:

With ammonium hydroxide; In benzene; at 0 ℃; for 0.0833333h; Yield given;

DOI:10.1016/S0040-4020(01)90408-9

Reference yield:

bromo-acetic acid amide (683-57-8) + para-thiocresol (106-45-6) → 2-(4-methylphenylsulfanyl)acetamide (73623-29-7)

Guidance literature:

With triethylamine; In diethyl ether; at 20 ℃; for 1h;

DOI:10.1016/j.tetasy.2008.01.021

Reference yield:

para-thiocresol (106-45-6) + Chloroacetamide (79-07-2) → 2-(4-methylphenylsulfanyl)acetamide (73623-29-7)

Guidance literature:

With sodium ethanolate;

upstream raw materials:

para-thiocresol

Chloroacetamide

(p-tolylthio)acetic acid chloride

bromo-acetic acid amide

Downstream raw materials:

2-(p-toluenesulfinyl)acetamide

2-p-tolylsulfanyl-thioacetamide

2-Chloro-2-(toluene-4-sulfinyl)-dodecanoic acid amide