3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide

Base Information

• Chemical Name: 3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide
• CAS No.: 1046825-17-5
• Molecular Formula: Br*C₂₂H₂₄N₅
• Molecular Weight: 438.37
• Mol file: 1046825-17-5.mol

Synonyms:3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide

Chemical Property of 3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide

There total 3 articles about 3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-mesityl-3-(prop-2-yn-1-yl)-1H-imidazol-3-ium bromide (960205-03-2) + benzyl bromide (100-39-0) → 3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide (1046825-17-5)

Guidance literature:

benzyl bromide; With sodium azide; In methanol; water; for 2h; Reflux;

1-mesityl-3-(prop-2-yn-1-yl)-1H-imidazol-3-ium bromide; With copper(ll) sulfate pentahydrate; sodium ascorbate; In methanol; water; at 20 ℃; for 24h;

DOI:10.1002/chem.201103631

Reference yield: 37.0%

1-mesityl-3-(prop-2-yn-1-yl)-1H-imidazol-3-ium bromide (960205-03-2) + benzyl azide (622-79-7) → 3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide (1046825-17-5)

Guidance literature:

With copper(ll) sulfate pentahydrate; ascorbate; In water; isopropyl alcohol; for 40h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c3dt51440d

Reference yield:

N-(2,4,6-trimethylphenyl)imidazole (25364-44-7) → 3-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1-mesityl-1H-imidazol-3-ium bromide (1046825-17-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene / Reflux

2.1: sodium azide / methanol; water / 2 h / Reflux

2.2: 24 h / 20 °C

With sodium azide; In methanol; water; toluene;

DOI:10.1002/chem.201103631

upstream raw materials:

1-mesityl-3-(prop-2-yn-1-yl)-1H-imidazol-3-ium bromide

benzyl bromide

N-(2,4,6-trimethylphenyl)imidazole

benzyl azide

Downstream raw materials:

1-mesityl-3-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]-1H-imidazol-3-ium hexafluorophosphate