1H-Imidazole, 1-(2,4,6-trimethylphenyl)-

Base Information

Chemical Name:1H-Imidazole, 1-(2,4,6-trimethylphenyl)-
CAS No.:25364-44-7
Molecular Formula:C12H14N2
Molecular Weight:186.257
Hs Code.:

Synonyms:

Suppliers and Price of 1H-Imidazole, 1-(2,4,6-trimethylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 8 raw suppliers

Chemical Property of 1H-Imidazole, 1-(2,4,6-trimethylphenyl)-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

General Description 1H-Imidazole, 1-(2,4,6-trimethylphenyl)-, also known as 1-mesitylimidazole, is a sterically hindered N-heterocyclic compound commonly used as a precursor for N-heterocyclic carbene (NHC) ligands in coordination chemistry and catalysis. It has been employed in the synthesis of metal-carbene complexes, such as iridium and palladium catalysts, demonstrating utility in polymerization and magnetization transfer applications. Additionally, derivatives of 1H-Imidazole, 1-(2,4,6-trimethylphenyl)-, like 1-mesityl-3-(2-naphthoylmethano)-1H-imidazolium bromide, exhibit antitumor activity against various cancer cell lines. Its steric bulk and electronic properties make it a versatile scaffold in organometallic and medicinal chemistry.

Technology Process of 1H-Imidazole, 1-(2,4,6-trimethylphenyl)-

There total 18 articles about 1H-Imidazole, 1-(2,4,6-trimethylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 131543-46-9,107-22-2
Glyoxal

: 6334-11-8
2,4,6-trimethylaniline hydrochloric acid salt

: 25364-44-7
N-(2,4,6-trimethylphenyl)imidazole

Guidance literature:: formaldehyd; Glyoxal; 2,4,6-trimethylaniline hydrochloric acid salt; With ammonium chloride; In 1,4-dioxane; water; at 100 ℃;

With sodium hydroxide; In 1,4-dioxane; water; at 0 ℃;
DOI:10.1016/j.tetlet.2010.07.097

Reference yield: 93.0%

: 91-22-5
quinoline

: 141556-45-8
1,3-bis(mesityl)imidazolium chloride

: 34557-54-5,27936-85-2
methane

: 1056451-44-5
2-(3,5-dimethylphenyl)-quinoline

: 25364-44-7
N-(2,4,6-trimethylphenyl)imidazole

Guidance literature:: With bis(1,5-cyclooctadiene)diiridium(I) dichloride; sodium t-butanolate; at 180 ℃; for 18h; Reagent/catalyst; Temperature; Glovebox; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.organomet.9b00338