(2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate
CAS No.:1126428-47-4
Molecular Formula:C₂₄H₄₀N₂O₃
Molecular Weight:404.593
Hs Code.:

Synonyms:(2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate

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Chemical Property of (2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate

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Technology Process of (2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate

There total 1 articles about (2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1126428-46-3
(S)-tert-butyl-2-(2-(4-tert-butylphenyl)acetyl)pyrrolidine-1-carboxylate

: 156-87-6
propan-1-ol-3-amine

: 1126428-47-4
(2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate

Guidance literature:: (S)-tert-butyl-2-(2-(4-tert-butylphenyl)acetyl)pyrrolidine-1-carboxylate; propan-1-ol-3-amine; With titanium(IV) isopropylate; In tetrahydrofuran; at 20 ℃;

With sodium tetrahydroborate; In tetrahydrofuran; methanol; for 2h;

Reference yield: 99.0%

: 1126428-47-4
(2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate

: 1126428-48-5
3-(2-(4-tert-butylphenyl)-1-((S)-pyrrolidin-2-yl)ethylamino)propan-1-ol

Guidance literature:: (2S)-tert-butyl-2-(2-(4-tert-butylphenyl)-1-(3-hydroxypropylamino)ethyl)pyrrolidine-1-carboxylate; With hydrogenchloride; In water; ethyl acetate; at 20 ℃; for 4h;

With potassium carbonate; In water; ethyl acetate; for 0.5h;