Iodolevetimide

Base Information

Chemical Name:Iodolevetimide
CAS No.:119477-44-0
Molecular Formula:C₂₃H₂₅IN₂O₂*ClH
Molecular Weight:524.829
Hs Code.:
UNII:CV29CQA7UV

Synonyms:4-(125I)iododexetimide;4-iododexetimide;4-iododexetimide, 123I-labeled;4-iododexetimide, 125I-labeled;4-iodolevetimide;4-iodolevetimide, 125I-labeled

Suppliers and Price of Iodolevetimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Iodolevetimide

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:488.09608
Heavy Atom Count:28
Complexity:561

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCC1C2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=C(C=C4)I
Isomeric SMILES:C1CN(CCC1[C@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=C(C=C4)I

Technology Process of Iodolevetimide

There total 3 articles about Iodolevetimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21888-99-3
Levetimide

: 119477-44-0
(R)-3-Phenyl-3-<1-<(4-iodophenyl)methyl>-4-piperidinyl>-2,6-piperidinedione hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, conc. aq. HCl / 5percent Pd/C / methanol / 72 h / 3102.9 Torr / Ambient temperature

2: 1) K₂CO₃, 2) HCl / 1) EtOH, reflux, 3 h, 2) Et₂O

With hydrogenchloride; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00125a021

Reference yield:

: 624-31-7
4-tolyl iodide

: 119477-44-0
(R)-3-Phenyl-3-<1-<(4-iodophenyl)methyl>-4-piperidinyl>-2,6-piperidinedione hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 49.7 percent / N-bromosuccinimide, benzoyl peroxide / CCl₄ / 3.5 h / Heating

2: 1) K₂CO₃, 2) HCl / 1) EtOH, reflux, 3 h, 2) Et₂O

With hydrogenchloride; N-Bromosuccinimide; Perbenzoic acid; potassium carbonate; In tetrachloromethane;
DOI:10.1021/jm00125a021