Technology Process of C23H25N5O3
There total 13 articles about C23H25N5O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C29H39N5O3Si;
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 20 ℃;
With
water;
In
tetrahydrofuran;
Product distribution / selectivity;
Cooling with ice;
- Guidance literature:
-
C28H33N5O4;
With
hydrogenchloride;
In
methanol; isopropyl alcohol;
at 10 - 20 ℃;
for 1h;
With
ammonium hydroxide;
In
methanol; water; isopropyl alcohol;
Product distribution / selectivity;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: trichlorophosphate / 2 h / 100 °C
1.2: Cooling with ice
2.1: sodium carbonate / triphenylphosphine; palladium diacetate / 1,2-dimethoxyethane; water / 4 h / Reflux
3.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere
4.2: 5 - 20 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C
5.2: Cooling with ice
With
tetrabutyl ammonium fluoride; sodium hydride; sodium carbonate; sodium t-butanolate; trichlorophosphate;
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; mineral oil;
