cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

Base Information

Chemical Name:cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde
CAS No.:1202008-49-8
Molecular Formula:C₁₉H₂₉FO₂Si
Molecular Weight:336.522
Hs Code.:

Synonyms:cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

Suppliers and Price of cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

There total 4 articles about cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1202007-00-8
cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexane-carbonitrile

: 1202008-49-8
cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

Guidance literature:: cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexane-carbonitrile; With diisobutylaluminium hydride; In dichloromethane; at -70 ℃; for 1.33333h;

With Rochelle's salt; In dichloromethane; water; at 20 ℃; for 2h;

Reference yield:

: 459-22-3
4-fluorophenylacetonitrile

: 1202008-49-8
cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium methylate / tetrahydrofuran; methanol / 20 - 50 °C

2.1: hydrogenchloride / ethanol; water / 40 h / Reflux

3.1: sodium tetrahydroborate / ethanol / -20 - 20 °C

4.1: 2,6-dimethylpyridine / dichloromethane / 0 - 20 °C

5.1: diisobutylaluminium hydride / dichloromethane / 1.33 h / -70 °C

5.2: 2 h / 20 °C

With 2,6-dimethylpyridine; hydrogenchloride; sodium tetrahydroborate; sodium methylate; diisobutylaluminium hydride; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;

Reference yield:

: 1202006-99-2
(1s,4s)-1-(4-fluorophenyl)-4-hydroxycyclohexanecarbonitrile

: 1202008-49-8
cis-4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexanecarbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: 2,6-dimethylpyridine / dichloromethane / 0 - 20 °C

2.1: diisobutylaluminium hydride / dichloromethane / 1.33 h / -70 °C

2.2: 2 h / 20 °C

With 2,6-dimethylpyridine; diisobutylaluminium hydride; In dichloromethane;