6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Base Information

Chemical Name:6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
CAS No.:67287-41-6
Molecular Formula:C₁₈H₂₀BrNO₂
Molecular Weight:362.266
Hs Code.:
DSSTox Substance ID:DTXSID701165210

Synonyms:SCHEMBL7331849;WUISFYZOKPXMQV-UHFFFAOYSA-N;DTXSID701165210;6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine;67287-41-6;6-Bromo-2,3,4,5-tetrahydro-7,8-dimethoxy-1-phenyl-1H-3-benzazepine

Suppliers and Price of 6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:361.06774
Heavy Atom Count:22
Complexity:348

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=C2CCNCC(C2=C1)C3=CC=CC=C3)Br)OC

Technology Process of 6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

There total 1 articles about 6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67287-41-6
6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Guidance literature:

Reference yield: 78.5%

: 67287-41-6
6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

: 1765-93-1
4-fluoroboronic acid

: 1080523-29-0
6-(4-fluorophenyl)-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride hydrate; sodium carbonate; In ethanol; water; toluene; at 100 ℃; for 36h; Inert atmosphere;
DOI:10.1016/j.bmc.2008.09.049

Reference yield: 39.0%

: 67287-41-6
6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

: 1679-18-1
4-Chlorophenylboronic acid

: 1080523-28-9
6-(4-chlorophenyl)-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride hydrate; sodium carbonate; In ethanol; water; toluene; at 100 ℃; for 36h; Inert atmosphere;
DOI:10.1016/j.bmc.2008.09.049