Methyl 6-amino-5-bromonicotinate

Base Information

Chemical Name:Methyl 6-amino-5-bromonicotinate
CAS No.:180340-70-9
Molecular Formula:C₇H₇BrN₂O₂
Molecular Weight:231.049
Hs Code.:2933399090
European Community (EC) Number:640-110-1
DSSTox Substance ID:DTXSID00377300
Wikidata:Q72486745
Mol file:180340-70-9.mol

Synonyms:Methyl 6-amino-5-bromonicotinate;180340-70-9;methyl 6-amino-5-bromopyridine-3-carboxylate;methyl-6-amino-5-bromonicotinate;3-Pyridinecarboxylic acid, 6-amino-5-bromo-, methyl ester;MFCD06659561;METHYL6-AMINO-5-BROMONICOTINATE;Methyl 2-amino-3-bromo-5-pyridinecarboxylate;Methyl 6-amino-5-bromo-pyridine-3-carboxylate;6-AMINO-5-BROMONICOTINIC ACID METHYL ESTER;SCHEMBL3346590;DTXSID00377300;LNTAAMVZKGYIIA-UHFFFAOYSA-N;AKOS005070726;AB25976;CS-W003325;SY006407;A3997;AM20070213;FT-0646963;EN300-316337;5Y-0703;W-206281;Z1269229201

Suppliers and Price of Methyl 6-amino-5-bromonicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl6-Amino-5-bromonicotinate
50mg
$ 45.00

SynQuest Laboratories
Methyl 6-amino-5-bromonicotinate
1 g
$ 29.00

SynQuest Laboratories
Methyl 6-amino-5-bromonicotinate
5 g
$ 120.00

Matrix Scientific
Methyl 6-amino-5-bromonicotinate >95%
1g
$ 304.00

Matrix Scientific
Methyl 6-amino-5-bromonicotinate >95%
500mg
$ 244.00

Matrix Scientific
Methyl 6-amino-5-bromonicotinate >95%
5g
$ 698.00

Crysdot
Methyl6-amino-5-bromonicotinate 97%
25g
$ 366.00

Chemenu
Methyl6-Amino-5-bromonicotinate 97%
25g
$ 365.00

Chemenu
Methyl6-Amino-5-bromonicotinate 97%
5g
$ 112.00

Chemenu
Methyl6-Amino-5-bromonicotinate 97%
10g
$ 194.00

Total 43 raw suppliers

Chemical Property of Methyl 6-amino-5-bromonicotinate

Chemical Property:

Melting Point:166-168 °C
Boiling Point:323.691 °C at 760 mmHg
PKA:2.02±0.49(Predicted)
Flash Point:149.563 °C
PSA：65.21000
Density:1.662 g/cm³
LogP:1.79410
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:229.96909
Heavy Atom Count:12
Complexity:177

Purity/Quality:

99%, ^*data from raw suppliers

Methyl6-Amino-5-bromonicotinate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(N=C1)N)Br

Technology Process of Methyl 6-amino-5-bromonicotinate

There total 3 articles about Methyl 6-amino-5-bromonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.8%

: 36052-24-1
methyl 6-aminonicotinoate

: 180340-70-9
methyl 6-amino-5-bromopyridine-3-carboxylate

Guidance literature:: With N-Bromosuccinimide; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

: 180340-69-6
6-Amino-5-bromopyridine-3-carboxylic acid

: 180340-70-9
methyl 6-amino-5-bromopyridine-3-carboxylate

Guidance literature:: In water; methanol hydrochloride;

Reference yield:

: 3167-49-5
6-aminonicotinic acid

: 180340-70-9
methyl 6-amino-5-bromopyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 0 - 80 °C

2: N-Bromosuccinimide / tetrahydrofuran / 0 - 20 °C

With N-Bromosuccinimide; sulfuric acid; In tetrahydrofuran;