allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

Base Information

Chemical Name:allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside
CAS No.:709669-19-2
Molecular Formula:C₂₆H₃₂FNO₆
Molecular Weight:473.542
Hs Code.:

Synonyms:allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

Suppliers and Price of allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

There total 5 articles about allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 709669-18-1
allyl 2-acetamido-2-deoxy-3-O-(4-methoxybenzyl)-6-O-benzyl-α-D-galactopyranoside

: 709669-19-2
allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

Guidance literature:: With pyridine; diethylamino-sulfur trifluoride; In dichloromethane; at -20 - 20 ℃;
DOI:10.1021/ol049598w

Reference yield:

: 72-87-7,1136-42-1,1136-44-3,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4,6082-29-7
N-acetyl-D-galactosamine

: 709669-19-2
allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / BF₃*Et₂O / 2 h / 70 °C

2: 75 percent / (+/-)-camphorsulfonic acid / dimethylformamide / 12 h / 20 °C

3: 66 percent / sodium hydride; tetrabutylammonium iodide / tetrahydrofuran / 6 h / 40 °C

4: 81 percent / NaBH₃CN; molecular sieves 4 Angstroem; HCl / tetrahydrofuran; diethyl ether / 1 h / 0 °C

5: 60 percent / (diethylamino)sulfur trifluoride; pyridine / CH₂Cl₂ / -20 - 20 °C

With pyridine; hydrogenchloride; diethylamino-sulfur trifluoride; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium cyanoborohydride; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol049598w

Reference yield:

: 64650-83-5
N-((2S,3R,4R,5R,6R)-2-Allyloxy-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-acetamide

: 709669-19-2
allyl 2-acetamido-2,4-dideoxy-3-O-(4-methoxybenzyl)-4-fluoro-6-O-benzyl-α-D-glucopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / (+/-)-camphorsulfonic acid / dimethylformamide / 12 h / 20 °C

2: 66 percent / sodium hydride; tetrabutylammonium iodide / tetrahydrofuran / 6 h / 40 °C

3: 81 percent / NaBH₃CN; molecular sieves 4 Angstroem; HCl / tetrahydrofuran; diethyl ether / 1 h / 0 °C

4: 60 percent / (diethylamino)sulfur trifluoride; pyridine / CH₂Cl₂ / -20 - 20 °C

With pyridine; hydrogenchloride; diethylamino-sulfur trifluoride; 4 A molecular sieve; camphor-10-sulfonic acid; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium cyanoborohydride; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol049598w