1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone

Base Information

• Chemical Name: 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone
• CAS No.: 1026806-53-0
• Molecular Formula: C₃₄H₄₄N₂O₃Si
• Molecular Weight: 556.82

Synonyms:1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone

Chemical Property of 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone

There total 5 articles about 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-Diphenylmethanol (91-01-0) → 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone (1026806-53-0)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂SO₄ / toluene / Heating

2: K₂CO₃ / toluene / 12 h / Heating

3: aq. NaHCO₃ / CHCl₃ / 0.17 h

With sulfuric acid; sodium hydrogencarbonate; potassium carbonate; In chloroform; toluene; 1: Condensation / 2: Alkylation / 3: Acylation;

DOI:10.1021/jm990291q

Reference yield:

p-Coumaric Acid (7400-08-0,50940-26-6) → 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone (1026806-53-0)

Guidance literature:

Multi-step reaction with 3 steps

1: imidazole / dimethylformamide / 20 °C

2: oxalyl chloride; DMF / CH₂Cl₂ / 2 h / 0 - 20 °C

3: aq. NaHCO₃ / CHCl₃ / 0.17 h

With 1H-imidazole; oxalyl dichloride; sodium hydrogencarbonate; N,N-dimethyl-formamide; In dichloromethane; chloroform; N,N-dimethyl-formamide; 1: silylation / 2: Chlorination / 3: Acylation;

DOI:10.1021/jm990291q

Reference yield:

1,1'-[(2-chloroethoxy)methylene]bis-benzene (32669-06-0) → 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone (1026806-53-0)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / toluene / 12 h / Heating

2: aq. NaHCO₃ / CHCl₃ / 0.17 h

With sodium hydrogencarbonate; potassium carbonate; In chloroform; toluene; 1: Alkylation / 2: Acylation;

DOI:10.1021/jm990291q

upstream raw materials:

1-[2-(diphenylmethoxy)ethyl]piperazine

1,1-Diphenylmethanol

p-Coumaric Acid

1,1'-[(2-chloroethoxy)methylene]bis-benzene

Downstream raw materials:

(E)-1-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-3-(4-hydroxy-phenyl)-propenone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1026806-53-0 1-[4-(2-benzhydryloxy-ethyl)-piperazin-1-yl]-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propenone

Send

Send

Metric Ton KG G Pound L ML

Send

Send