diethyl dimethylmalonate-d₆

Base Information

• Chemical Name: diethyl dimethylmalonate-d₆
• CAS No.: 14575-07-6
• Molecular Formula: C₉H₁₆O₄
• Molecular Weight: 194.176
• Mol file: 14575-07-6.mol

Synonyms:diethyl dimethylmalonate-d₆

Chemical Property of diethyl dimethylmalonate-d₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl dimethylmalonate-d₆

There total 2 articles about diethyl dimethylmalonate-d₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iodomethane-d3 (865-50-9) + diethyl malonate (105-53-3) → diethyl dimethylmalonate-d6 (14575-07-6) + [2H3]methylmalonic acid (42522-59-8)

Guidance literature:

diethyl malonate; With sodium hydride; In N,N-dimethyl-formamide; at 55 ℃;

iodomethane-d3; In N,N-dimethyl-formamide; at 60 ℃; for 1h;

With potassium hydroxide; for 3h; Heating;

DOI:10.1002/jlcr.1034

Reference yield:

iodomethane-d3 (865-50-9) + diethyl malonate (105-53-3) → diethyl 2-[methyl-2H3]methylmalonate (54840-57-2) + diethyl dimethylmalonate-d6 (14575-07-6)

Guidance literature:

diethyl malonate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

iodomethane-d3; In tetrahydrofuran; for 2h; Title compound not separated from byproducts; Heating;

DOI:10.1002/jlcr.881

Reference yield:

diethyl dimethylmalonate-d6 (14575-07-6) → 2-<(2)H3>methyl-<3,3,3-(2)H3>propanoic acid (29054-08-8)

Guidance literature:

With water; lithium chloride; In dimethyl sulfoxide; for 6h; Heating;

DOI:10.1039/P29870000385

upstream raw materials:

iodomethane-d3

diethyl malonate

Downstream raw materials:

2-<(2)H3>methyl-<3,3,3-(2)H3>propanoic acid