1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Base Information

• Chemical Name: 1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
• CAS No.: 121208-37-5
• Molecular Formula: C₁₇H₁₅FN₂
• Molecular Weight: 266.318
• Mol file: 121208-37-5.mol

Synonyms:1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Chemical Property of 1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

There total 2 articles about 1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride → 1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (121208-37-5)

Guidance literature:

With sodium carbonate; In water;

DOI:10.1002/chem.202004449

Reference yield:

[1-(2-Fluoro-phenyl)-meth-(E)-ylidene]-[2-(1H-indol-3-yl)-ethyl]-amine → 1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (121208-37-5)

Guidance literature:

With sulfuric acid; at 50 ℃; for 48h;

DOI:10.1007/s10593-007-0093-y

Reference yield: 73.0%

1-(2-fluorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole (121208-37-5) + ethyl iodide (75-03-6) → C19H19FN2 (1034153-29-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 4h;

DOI:10.1007/s10593-007-0093-y

Downstream raw materials:

C₁₉H₁₉FN₂