N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

Base Information

Chemical Name:N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide
CAS No.:157567-13-0
Molecular Formula:C₂₀H₂₈N₂O₄S
Molecular Weight:392.519
Hs Code.:

Synonyms:N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

Suppliers and Price of N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

Chemical Property:

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Technology Process of N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

There total 9 articles about N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 799241-81-9
N-(3-dibenzylamino-2-hydroxy-4-phenyl-butyl)-4-hydroxy-N-isobutyl-benzenesulfonamide

: 157567-13-0
N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃;
DOI:10.1021/jm049560p

Reference yield:

: 799241-79-5
N-((2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide

: 157567-13-0
N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: BBr₃ / CH₂Cl₂

2: H₂ / Pd/C / methanol / 20 °C

With hydrogen; boron tribromide; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm049560p

Reference yield:

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 157567-13-0
N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-4-hydroxy-N-isobutylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 4 h / 20 °C

2: BBr₃ / CH₂Cl₂

3: H₂ / Pd/C / methanol / 20 °C

With hydrogen; boron tribromide; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm049560p